نتایج جستجو برای: colony stimulating factor stxa1

تعداد نتایج: 918129  

Journal: :The Journal of biological chemistry 1993
T Hoang A De Léan A Haman V Beauchemin T Kitamura S C Clark

Myeloid cell lines and primary leukemic myeloblasts express two classes of granulocyte macrophage colony-stimulating factor (GM-CSF) binding sites of high (Kd 20-50 pM) and low affinity (Kd 5-10 nM). High affinity binding is caused by the association of two chains, p80 alpha and p130 beta, whereas p80 alpha alone confers low affinity binding only. Furthermore interleukin-3 (IL-3) competes for t...

Journal: :The Journal of Experimental Medicine 1990
Jonathan L. McQualter Rima Darwiche Christine Ewing Manabu Onuki Thomas W. Kay John A. Hamilton Hugh H. Reid Claude C.A. Bernard

Experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis, can be induced by immunization with a number of myelin antigens. In particular, myelin oligodendrocyte glycoprotein, a central nervous system (CNS)-specific antigen expressed on the myelin surface, is able to induce a paralytic MS-like disease with extensive CNS inflammation and demyelination in several strains of ...

Journal: :The Laryngoscope 2013
Shin Kariya Mitsuhiro Okano Takaya Higaki Seiichiro Makihara Takenori Haruna Motoharu Eguchi Kazunori Nishizaki

OBJECTIVES/HYPOTHESIS Granulocyte/macrophage colony-stimulating factor is important in the pathogenesis of acute and chronic inflammatory disease. We hypothesized that granulocyte/macrophage colony-stimulating factor plays a pivotal role in middle ear inflammation and that neutralization of granulocyte/macrophage colony-stimulating factor would inhibit neutrophil migration into the middle ear a...

2013
H. P. Koeffler

We show that 1,25-dihydroxyvitamin D3 (1,25[0H12D3), the most hormonally active metabolite of vitamin 113, modulates sensitively and specifically both the protein and messenger RNA accumulation of the multilineage growth factor granulocyte-macrophage colony-stimulating factor (GM-CSF). The regulation of GMCSF expression is seen in both normal human mitogen-activated T lymphocytes and T lymphocy...

Journal: :Infectious Diseases in Obstetrics and Gynecology 1995

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