Small molecules have been identified as potential therapeutic agents for lysosomal storage diseases (LSDs), inherited metabolic disorders caused by defects in proteins that result in lysosome dysfunctional. Some small molecules function assisting the folding of mutant misfolded lysosomal enzymes that are otherwise degraded in ER-associated degradation. The ultimate result is the enhancement of ...

This work is related to the characterization of nanometrics materials ?MnMoO4-?CoMoO4 system, prepared by co-precipitation and sol-gel routes from corresponding metal salts. The structural, morphological colorimetric characteristics obtained powders were studied using thermogravimetric differential thermal analysis (TGA-DTA), X-ray diffraction (XRD), infrared Raman spectroscopy, scanning electr...

The development of new sensitive, cost-effective and user-friendly colorimetric bioassays is in increasing demand to meet the requirement of modern clinical diagnostics and field detection. Herein, a novel iron oxide-to-Prussian blue (PB) nanoparticle (NP) conversion strategy was developed and applied to sensitive colorimetric immunosensing of cancer biomarkers. In a typical sandwich-type immun...

The RGB signals generated by different cameras are not equal for the same scene. Therefore, cameras are characterized based on a CIE standard colorimetric observer. One method of deriving a colorimetric characterization matrix between camera RGB output signals and CIE XYZ tristimulus values is least squares polynomial modeling. Yet, this involves tedious experiments to obtain a camera transfer ...

Spectrophotometric measurement applied on saturated granular activated carbon (GAC) is not yet explored. A colorimetric method in the visible range has been developed in order to determine the exhaustion level of GAC used in rum production. Aqueous ammonia solution has been used as an indicative agent to determine the extraction rate of taste compounds within the rum production process and the ...

An algorithm is proposed for the spectral and colorimetric characterization of digital still cameras (DSC) which allows them to be used as tele-colorimeters with CIE–XYZ color output, in cd/m2. The spectral characterization consists in the calculation of the color-matching functions from the previously measured spectral sensitivities. The colorimetric characterization consists in transforming t...

We describe two fully enzymic methods, fluorometric and colorimetric, for determination of triglycerides (triacylglycerols) in serum. Samples are incubated with microbial lipase for 10 min, and the glycerol released from the triglycerides is oxidized by NAD+ in the presence of glycerol dehydrogenase. In the fluorometric method, the resulting NADH is in turn oxidized by resazurin as catalyzed by...

BACKGROUND Estimation of urinary oxalate is one of important tools for the diagnosis and treatment of urolithiasis. And more precise, simple and inexpensive method is desirable. In the present study, we evaluated three methods which were clinically well-used. METHODS From October 1996 to June 1997, 146 acidified urine samples were collected for 24 hours from 144 urolithiasis patients. We dete...