INTRODUCTION Primary ectatic corneal diseases usually require rigid gas-permeable (RGP) corneal contact lens wear for visual rehabilitation. As the disease progresses, it becomes increasingly difficult to fit these lenses. RGP scleral contact lenses now provide another treatment option before resorting to surgery. CLINICAL PICTURE Two patients with pellucid marginal degeneration and one with ...

Silicate nanoparticle; Corneal neovascularisation; Vascular endothelial growth factor Abstract Corneal neo-vascularisation (NV) is a major sight-threatening condition and is caused by infections, degenerative disorders, inflammation and long-time contact lens wear. Corneal NV occurs when the balance between angiogenic and antiangiogenic factors is tipped towards angiogenic molecules. The abnorm...

PURPOSE OF REVIEW To highlight the most important causes of acquired corneal scarring and infiltrates in children. The lack of recognition of these disorders can lead to long-term visual loss in children. RECENT FINDINGS There have been few articles on this topic in the recent ophthalmic literature, but all have stressed the need for early diagnosis and treatment of these diseases. SUMMARY ...

Over the last decade there has been a paradigm shift from penetrating keratoplasty (PKP) to lamellar keratoplasty for the management of primary as well as acquired corneal ectasia. Several treatment modalities have emerged including collagen cross-linking, intrastromal implants, laser vision correction, and recent techniques in central and peripheral lamellar keratoplasty. This article reviews ...

A solution to get the problem off, have you found it? Really? What kind of solution do you resolve the problem? From what sources? Well, there are so many questions that we utter every day. No matter how you will get the solution, it will mean better. You can take the reference from some books. And the excimer laser surgery for corneal disorders is one book that we really recommend you to read,...

Human corneal endothelial cells (HCEnCs) form a monolayer of hexagonal cells whose main function is to maintain corneal clarity by regulating corneal hydration. HCEnCs are derived from neural crest and are arrested in the post-mitotic state. Thus cell loss due to aging or corneal endothelial disorders leads to corneal edema and blindness-the leading indication for corneal transplantation. Here ...

Various clinical disorders and injuries, such as chemical, thermal, or mechanical injuries, may lead to corneal loss that results in blindness. PURPOSE: The aims of this study were to differentiate human buccal mucosa (BMuc) into corneal epithelial-like cells, to fabricate engineered corneal tissue using buccal mucosal epithelial cells, and to reconstruct a damaged corneal epithelium in a nude ...