PURPOSE To study the effect of mitomycin C (MMC) on the corneal regrowth after laser-assisted sub-epithelial keratectomy (LASEK). METHODS We performed a prospective, controlled, observer-masked study of 64 consecutive eyes scheduled to undergo LASEK to correct their myopia. The patients were divided into two age-matched groups, with group 1 including 32 eyes in which the ablation depth was ≤ ...

Epithelial basement membrane dystrophy (EBMD) is the most common corneal dystrophy seen in clinical practice. Its appearance varies, which leads to frequent misdiagnosis, but presentation most often includes dot-like epithelial opacities, whorl-like fingerprint lines and circumscribed gray map-like patterns. It is for this reason that EBMD is also referred to as a map-dot-fingerprint dystrophy....

In this study we report on the effects of constant light (CL) on the refractive development and ocular morphology of White Leghorn chicks (Cornell K-strain). Refractive state and corneal curvature were measured by IR photoretinoscopy and IR keratometry respectively. The axial lengths of the ocular components were measured by A-scan ultrasonography. We find that constant light produces significa...

In the present study, the effects of the acute and chronic oral administrations (po) of curcumin in the absence and presence of morphine and naloxone was investigated on the sensation of acute corneal pain in rats. Acute corneal pain was induced by the local application of hypertonic saline (5 M NaCl) on the corneal surface, and the number of eye wipes was then counted for 30 s. Subcutaneous (s...

PURPOSE To longitudinally follow epithelial thickness profile changes after myopic LASIK for 1 year to determine when and how epithelial changes occur and when epithelial stability is reached. METHODS Epithelial thickness was measured with Artemis very high-frequency digital ultrasound (ArcScan Inc) across the central 10-mm corneal diameter in 11 eyes before and 1 day, and 1, 3, 6, and 12 mon...