نتایج جستجو برای: curcumin nano formulations

تعداد نتایج: 98866  

2017
Jong-Suep Baek Cheong-Weon Cho

The objective of the work was to develop a multifunctional nanomedicine based on a folate-conjugated lipid nanoparticles loaded with paclitaxel and curcumin. The novel system combines therapeutic advantageous of efficient targeted delivery via folate and timed-release of curcumin and paclitaxel via 2-hydroxypropyl-ß-cyclodextrin, thereby overcoming multidrug resistance in breast cancer cells (M...

2017
Sultan Tousif Dhiraj Kumar Singh Sitabja Mukherjee Shaheer Ahmad Rakesh Arya Ranjan Nanda Anand Ranganathan Maitree Bhattacharyya Luc Van Kaer Santosh K. Kar Gobardhan Das

Curcumin, the bioactive component of turmeric also known as "Indian Yellow Gold," exhibits therapeutic efficacy against several chronic inflammatory and infectious diseases. Even though considered as a wonder drug pertaining to a myriad of reported benefits, the translational potential of curcumin is limited by its low systemic bioavailability due to its poor intestinal absorption, rapid metabo...

Journal: :International journal of oncology 2008
Rajesh L Thangapazham Anu Puri Shrikant Tele Robert Blumenthal Radha K Maheshwari

We have initiated studies to enhance targeted delivery of an anticancer agent, curcumin, for prostate cancer treatment by incorporating this agent into the liposomes (nanodelivery vehicles primarily composed of phospholipids) coated with prostate membrane specific antigen specific antibodies. We prepared curcumin-loaded liposomes of various lipid compositions by sonication at an average size of...

خیری منجیلی, حمیدرضا, دانافر, حسین, شرفی, علی, عطاری, الهه,

Background and Objective: Curcumin is a polyphenolic anti-cancer and anti-inflammatory agent and can be used both orally and by injection. In this study, nanoparticles of silica mesopore- gold nano were synthesized as a new drug delivery system. For this aim, gold nanoparticles as a promising system for effective drug delivery of curcumin was used and nano gold were delivered to breast cancer c...

Introdution: The aim of this research was optimization curcumin characteristics for oral hygiene application. Curcumin-loaded starch nano-particles were developed for enhancing adhesion propery with enamel surface and best anti-bacterial effect against Streptococcus mutans. Methods: The study was the experimental one. The nanoparticles synthesize was based on precipitation and ionic gelation m...

Journal: :Anticancer research 2013
Takuro Kurita Yuji Makino

Curcumin, a natural polyphenolic compound derived from turmeric (Curcuma longa L), has proven to be a modulator of multiple intercellular signalling pathways linked to inflammation, to proliferation, growth, invasion, drug sensitivity, angiogenesis and metastasis of cancer cells. Although curcumin has shown significant efficacy in cell culture studies, it has shown limited efficacy in clinical ...

Journal: :Biological & pharmaceutical bulletin 2011
Hiroki Sasaki Yoichi Sunagawa Kenji Takahashi Atsushi Imaizumi Hiroyuki Fukuda Tadashi Hashimoto Hiromichi Wada Yasufumi Katanasaka Hideaki Kakeya Masatoshi Fujita Koji Hasegawa Tatsuya Morimoto

Curcumin is a polyphenol that is commonly used for its perceived health benefits. However, the absorption efficacy of curcumin is too low to exhibit beneficial effects. We have successfully developed a highly absorptive curcumin dispersed with colloidal nano-particles, and named it THERACURMIN. The absorption efficacy of THERACURMIN was investigated and compared with that of curcumin powder. Th...

Journal: :Journal of Rafsanjan University of Medical Sciences 2023

The Effect of Endurance Training with Nano-Curcumin Supplementation on p53-p21 Axis and TERF2 Gene Expression in Muscle Tissue Male Wistar Rats: An Experimental Study

2018
Martin Purpura Ryan P Lowery Jacob M Wilson Haider Mannan Gerald Münch Valentina Razmovski-Naumovski

PURPOSE The optimal health benefits of curcumin are limited by its low solubility in water and corresponding poor intestinal absorption. Cyclodextrins (CD) can form inclusion complexes on a molecular basis with lipophilic compounds, thereby improving aqueous solubility, dispersibility, and absorption. In this study, we investigated the bioavailability of a new γ-cyclodextrin curcumin formulatio...

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