A novel norsesquiterpene, named norcyperone (1), and three known compounds: (-)-clovane-2,9-diol (2), rosenonolactone (3), and 5 alpha,8 alpha-epidioxy-(20S,22E,24R)-ergosta-6,22-dien-3beta-ol (4) were isolated from the rhizomes of Cyperus rotundus L. The structure of 1 was elucidated as 8,11,11-trimethylbicyclo[5.3.1]undecane-5 alpha, 8 alpha-epoxy-3-one on the basis of extensive spectroscopic...

Four sesquiterpenes, beta-selinene, isocurcumenol, nootkatone and aristolone and one triterpene, oleanolic acid were isolated from the ethylacetate fraction of the rhizomes of Cyperus rotundus and tested for their ability to modulate gamma-aminobutyric acid (GABA(A))-benzodiazepine receptor function by radioligand binding assays using rat cerebrocortical membranes. Among these compounds, only i...

The genus Cyperus belongs to tribe Cypereae, subfamily Cyperoideae and family Cyperaceae that is the largest genus in this family after Carex. The classification of genus Cyperus is still unsettled because of morphological variations and therefore, makes determination of subgenera boundaries and species difficult. In Flora Iranica (KUKKONEN 1998) this genus was divided to six subgenera. In this...

BACKGROUND Cyperus rotundus Linn. (Cyperaceae) is used to treat inflammation, pain, fever, wounds, boils and blisters in folk medicine. This study evaluated the antinociceptive effect of the hydromethanol extract of whole plant of C. rotundus (HMCR). METHODS The antinociceptive activity of HMCR was investigated in thermal-induced (hot plate and tail immersion) and chemical-induced (formalin) ...

Cyperus platycaulis is used in folk medicine in Kano, northern Nigeria, for the treatment of cold, cough, (tuberculosis), chest congestion, asthma, sneezing, and catarrh. The tuberous fragrant herb (black species) was extracted using ethanol, chloroform, n-butane, and n-hexane, to determine the physico-chemical properties of the plant and the cytotoxicity of the extracts with reference to its a...