David Smyth is a plant developmental geneticist. He began his independent career at Monash University in Melbourne in 1974, where he investigated the basis of the very large genomes of the true lilies (Lilium species) when DNA cloning methods became available. Two abundant dispersed elements turned out to be retrotransposons, revealing their important role in bulking up some plant genomes. In 1...

R700 Current Biology 25, R693–R710, Augu Ballard roots his development in the language of computation, the only tool available with which we can express the full breadth of necessary concepts, from mathematics to logic, representations, input and output, algorithms, control, systems, memory, interaction, and more (see also [8]). He uses this full breadth of computational methodologies far more ...

Recent evidence suggests that nearly 25% of U.S. adults (47 million) suffer from some level of sleep deprivation. The impact of this sleep deprivation on the U.S. economy includes direct medical expenses related to sleep deprivation and related disorders, the cost of accidents, and the cost of reduced worker productivity. Sleep research has examined the effects of sleep deprivation on a number ...

and others developed quantitative ways of coping, well before the photon had been conceived. Photon scattering can now accommodate all scattering phenomena, but as Johnsen points out, it is computationally messy. Chapter six is a tough one for those of us who belong to the rays and waves tradition. It includes transparency, reflection and refraction but is titled simply ‘Scattering with interfe...

ion representations such as differing prosodic templates (Crowhurst 1992, Prieto 1992) and constraint reranking (Colina 2003) have been proposed to account for these differences, as have different morphological parses (Bermúdez-Otero 2007). There are however, some concrete characteristics that are related to the dialectal differences such as whether the stem contains the diphthongs [je] and [we...

The CellLineNavigator database, freely available at http://www.medicalgenomics.org/celllinenavigator, is a web-based workbench for large scale comparisons of a large collection of diverse cell lines. It aims to support experimental design in the fields of genomics, systems biology and translational biomedical research. Currently, this compendium holds genome wide expression profiles of 317 diff...

Each year, the International Society for Computational Biology (ISCB; http:// www.iscb.org) gives two major awards to leaders and innovators in the field of bioinformatics. The awards committee, composed of current and past directors of the Society and previous award winners, has announced that the 2008 Accomplishment by a Senior Scientist Award will be given to David Haussler of the University...

Protein-leucine Ingestion Activates a Regenerative Inflammo-Myogenic Transcriptome in 1 Skeletal Muscle Following Intense Endurance Exercise 2 3 David S. Rowlands, Andre R. Nelson, Frederic Raymond, Sylviane Metairon, Robert 4 Mansourian, Jim Clarke, Trent Stellingwerff, Stuart M. Phillips 5 6 School of Sport and Exercise and Institute of Food Nutrition, and Human Health, Massey University, 7 W...

The differences in molecular mechanisms between osteochondroma and bizarre parosteal osteochondromatous proliferation (BPOP) remain to be fully elucidated. In the present study, the differentially expressed genes between BPOP and osteochondroma were obtained from the Gene Expression Omnibus online database, and the associations among these genes were analyzed using the Database for Annotation, ...

Richard G. FitzJohn†, Matthew W. Pennell*†, Amy E. Zanne, Peter F. Stevens, David C. Tank and William K. Cornwell Biodiversity Research Centre and Department of Zoology University of British Columbia, Vancouver, BC V6G 1Z4, Canada; Department of Biological Sciences Macquarie University, Sydney, NSW 2109, Australia; Department of Biological Sciences and Institute for Bioinformatics and Evolution...