This study aimed to investigate the effects of propolis-containing mucoadhesive gel in experimentally induced periodontitis rats. Propolis-containing was prepared by using chitosan with a modified mechanical method. Thirty-five Sprague Dawley rats were used study. Rats divided five groups as negative control, + 50 mg/dl propolis, 100 and healthy control. Experimental placing ligatures on inferi...

The present study investigated the role of the renal nerves in mediating the cardiovascular and renal responses produced by the central administration of the opioid-like peptide orphanin FQ/nociceptin (OFQ/N) in conscious Sprague-Dawley rats. In conscious rats, OFQ/N (10 μg icv) produced a transient bradycardia and hypotension (nadir 20 min). Although renal sympathetic nerve activity (RSNA) ini...

OBJECTIVE This study aimed to investigate the effect of masticatory functional changes on the lateral view morphology of the mandible in adult rats. DESIGN Sixty 21-day-old male Sprague-Dawley rats were divided into two groups. Sixteen received ordinary (hard) food during the whole experimental period (normal group). The remaining 44 received a soft diet during 21 weeks to develop a hypofunct...

Extremely low-frequency magnetic field (ELF-MF) has been suggested to influence the cognitive capability but this should be dynamically evaluated in a longitudinal study. Previous training can affect performance, but the influence under magnetic field is unclear. This study aims to evaluate the effects of previous training and ELF-MF exposure on learning and memory using the Morris water maze (...

Unrestrained male Sprague-Dawley rats were infused for seven days with a low (2.45 micrograms/hr) or high (9.81 micrograms/hr) concentration of E. coli lipopolysaccharide (LPS). Compared to control (saline-infused) rats, food intake in the LPS-infused rats remained depressed for the entire infusion period. Despite this long-term suppression of food intake, fever was observed only during the day...

We measured renal, splenogastric, and lumbar multiunit sympathetic activities in chloralose-anesthetized, paralyzed, and artificially respired Sprague-Dawley rats. Acute spinal transection reduced arterial pressure and lumbar sympathetic activity. However, renal and splenogastric activities were doubled after transection. We conclude that spinal systems exist in the rat that are capable of main...

Background: Stress disturbs body weight and food intake, but the core mechanisms are not well understood. Study design: Experimental Materials Methods: The study was conducted in National Institute of Health (NIH), Islamabad Sixty male Sprague Dawley rats (mean wt 250 ± 50 grams) were used divided into 2 groups. Each group comprised 30 rats. Group I taken as control. II exposed to chronic stres...

We investigated the influence of Mg feeding frequency on the variation in serum Mg concentration and tissue Mg levels in Mg-deficient rats. Sprague-Dawley rats, which had been fed a Mg-deficient diet for 14 d, were divided into 3 groups that were kept on 3 diets differing in their Mg content. The rats were fed 0.5-fold (Mg250 group), 1-fold (Mg500 group), or 1.5-fold (Mg750 group) the amounts o...

Prior work suggests that spinal systems are sensitive to the stimulus relationships that underlie Pavlovian conditioning. We studied this phenomenon in Sprague-Dawley rats by pairing a vibrotactile conditioned stimulus (CS) with a tailshock unconditioned stimulus (US). Experiment 1 showed that spinal rats exhibit differential conditioning, having longer tail-flick latencies on the tail-flick te...