AIMS Pulmonary vein isolation (PVI) by catheter ablation for atrial fibrillation (AF) requires suppression of patient restlessness by sufficient sedation in addition to maintaining stable respiration. We applied adaptive-servo ventilation (ASV) and examined the effects of ASV combined with deep propofol sedation on PVI using a NavX. METHODS AND RESULTS We analysed 75 paroxysmal AF (PAF) patie...

Over the last 10 years, there has been an explosion of literature surrounding sedation management for critically ill patients. The clinical target has moved away from an unconscious and immobile patient toward a goal of light or no sedation and early mobility. The move away from terms such as 'sedation' toward more patient-centered and symptom-based control of pain, anxiety, and agitation makes...

Delivery of safe but effective sedation can be a challenge for the endoscopist. Complications include respiratory depression, aspiration and cardiac arrhythmias, and the cardiopulmonary mortality of endoscopy may exceed that of general anesthesia. To administer sedation properly, it is necessary for endoscopists to understand the definitions and hazards of conscious versus deep sedation, the ro...

uria, despite an absence of relevant clinical manifestations. Although many health care providers realize that excessive antimicrobial use can be harmful and should be avoided, some clearly need to be reminded about the complete absence of evidence supporting antimicrobial therapy for abnormal urinalysis findings in patients who lack genitourinary symptoms and of the importance of adjusting tre...

This study estimates the frequency of different medical end-of-life decisions (ELDs) made in the United Kingdom (UK) in 2007-2008, comparing these with 2004. Postal survey was carried out with 8857 medical practitioners, of whom 3733 (42%) practitioners replied, with 2869 having attended a person who died in the previous year. The proportion of UK deaths involving (1) voluntary euthanasia (0.21...

The risk for cardiovascular complications while providing any level of sedation or general anesthesia is greatest when caring for patients already medically compromised. It is reassuring that significant untoward events can generally be prevented by careful preoperative assessment, along with attentive intraoperative monitoring and support. Nevertheless, providers must be prepared to manage unt...

Management of children and adolescents with congenital heart disease during cardiac catheterization is a challenge for the attending anaesthetist. According to other diagnostic procedures such as CT-scan and MRT, it is not always necessary to perform general anaesthesia with intubation. The aim of the anaesthesiologic management is to facilitate cardiac catheterization under physiological condi...

Purpose The American Academy of Pediatric Dentistry (AAPD) recognizes that there are pediatric dental patients for whom routine dental care using nonpharmacologic behavior guidance techniques is not a viable approach.1 The AAPD intends this guideline to assist the dental practitioner who elects to use anesthesia personnel for the administration of deep sedation/general anesthesia for pediatric ...

Consciousness has been related to the amount of integrated information that the brain is able to generate. In this paper, we tested the hypothesis that the loss of consciousness caused by propofol anesthesia is associated with a significant reduction in the capacity of the brain to integrate information. To assess the functional structure of the whole brain, functional integration and partial c...

INTRODUCTION Non-anaesthesiologist-administered propofol sedation (NAPS/NAAP) is increasingly used in many countries. Most regimens aim for light or moderate sedation. Little evidence on safety of deep NAPS sedation is available. The aim of this study was to explore the safety of intermittent deep sedation with NAPS in patients undergoing gastroenterologic endoscopic procedures. METHODS This ...