BACKGROUND Scientific literature can contain errors. Discrepancies, defined as two or more statements or results that cannot both be true, may be a signal of problems with a trial report. In this study, we report how many discrepancies are detected by a large panel of readers examining a trial report containing a large number of discrepancies. METHODS We approached a convenience sample of 343...

The ideal genetic analysis of family data would include whole genome sequence on all family members. A strategy of combining sequence data from a subset of key individuals with inexpensive, genome-wide association study (GWAS) chip genotypes on all individuals to infer sequence level genotypes throughout the families has been suggested as a highly accurate alternative. This strategy was followe...

Autopsies are the gold standard for diagnostic accuracy; however, no recent study has analyzed autopsies in heart failure (HF).We reviewed 1241 autopsies (January 2000-May 2005) and selected 232 patients with HF. Clinical and autopsy diagnoses were analyzed and discrepancies categorized according to their importance regarding therapy and prognosis.Mean age was 63.3 ± 15.9 years; 154 (66.4%) pat...

introduction: marginal adaptation of cast restorations is essential for their long-term success. as dentists usually assign ditching of dies to laboratory technicians, and ditching has a significant effect on marginal adaptation, the aim of this study was to compare ditching by laboratory technicians and standard approach on marginal adaptation of cast restoration. materials and methods: in thi...

Several self theories explore the effects of discrepant self-beliefs on motivation and emotion. This research intersected two self theories: self-discrepancy theory and objective self-awareness theory. Self-discrepancy theory predicts that ideal and ought discrepancies cause different negative emotions; objective self-awareness theory predicts that high self-awareness will strengthen the relati...

We give an upper bound for the minimal discrepancies of hypersurface singularities. As an application, we show that Shokurov’s conjecture is true for log-terminal threefolds.

The concept of discrepancy plays an important rôle in the study of uniformity properties of point sets. For sets of random points, the discrepancy is a random variable. We apply techniques from quantum field theory to translate the problem of calculating the probability density of (quadratic) discrepancies into that of evaluating certain path integrals. Both their perturbative and non-perturbat...

Experimental tests of quantum electro-dynamics (QED) have developed dramatically for simple atomic systems such as hydrogen. However, a range of anomalies has been discovered recently. There has also been significant progress for medium-Z hydrogenic and helium-like atoms. In this area tests are often based on X-ray spectroscopic measurements. Future prospects for critical insight into the natur...