نتایج جستجو برای: disease activity score 28

تعداد نتایج: 2762078  

Background and purpose: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by synovitis, inflammation, and joint destruction that if not well controlled can destroy cartilage, bone, ligaments and tendons, and in some cases cause disability. The aim of this study was to evaluate the possible role of the ratio of neutrophil-lymphocyte (NLR) as an inflammatory mar...

2012
Jeffrey R Curtis Annette H van der Helm-van Mil Rachel Knevel Tom W Huizinga Douglas J Haney Yijing Shen Saroja Ramanujan Guy Cavet Michael Centola Lyndal K Hesterberg David Chernoff Kerri Ford Nancy A Shadick Max Hamburger Roy Fleischmann Edward Keystone Michael E Weinblatt

OBJECTIVE Quantitative assessment of disease activity in rheumatoid arthritis (RA) is important for patient management, and additional objective information may aid rheumatologists in clinical decision making. We validated a recently developed multibiomarker disease activity (MBDA) test relative to clinical disease activity in diverse RA cohorts. METHODS Serum samples were obtained from the I...

2013
Ehab Mudher Mikhael Faiq Isho Gorial

Objective: Rheumatoid arthritis is a common autoimmune disease associated with many complications like joint damage, disability and even death. It requires early and aggressive treatment with regular follow up to ensure safety and effectiveness of treatment for the patients. Disease activity score of 28 joints (DAS28) and simplified disease activity index (SDAI) are common tools that used to as...

Journal: :Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 2015
Anna Raczkiewicz Bartłomiej Kisiel Maciej Kulig Witold Tłustochowicz

BACKGROUND Vitamin D deficiency is common in rheumatoid arthritis (RA) and may be related to disease activity. Population-based studies have shown the influence of vitamin D deficiency on quality of life (QoL), but it was not investigated in RA patients. OBJECTIVES The aim of the study was to determine possible relationship between vitamin D deficiency, QoL, physical activity (PA), and diseas...

Journal: : 2023

Background: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease. Inflammation leads to endothelial cells activation. Activated with increased leukocytes adhesion molecules expression, which can induce dysfunction (ED) and atherosclerosis.
 Aim: measure the serum level of Human cell-specific molecule-1 (endocan) in patients rheumatoid evaluate its relation Materials metho...

Journal: :Annals of the Rheumatic Diseases 2004

2011
Lodewijk de Groot Helmy Hinkema Johanna Westra Andries J Smit Cees GM Kallenberg Marc Bijl Marcel D Posthumus

INTRODUCTION Advanced glycation end products (AGEs) are produced and can accumulate during chronic inflammation, as might be present in patients with rheumatoid arthritis (RA). AGEs are involved in the development of cardiovascular disease. The aim of this study is to evaluate whether AGEs are increased in patients with long-standing RA and whether AGE accumulation is related to disease activit...

2014
Despoina Dimopoulou Maria Trachana Polyxeni Pratsidou-Gertsi George Garyfallos Prodromos Sidiropoulos Athina Theodoridou Alexandros Garyfallos

Methods A total of 96 (66 females) patients were enrolled. Psychosocial distress was assessed by the Greek version of the self-completed paper-based General Health Questionnaire (GHQ-28). A second questionnaire regarding marital status, education level and employment status was completed by all patients. Disease activity status at the last follow-up visit was assessed according to the Wallace’s...

Journal: :Arthritis & rheumatology 2016
Roy Fleischmann Sean E Connolly Michael A Maldonado Michael Schiff

OBJECTIVE To assess the ability of a multi-biomarker disease activity (MBDA) test (Vectra DA) to reflect clinical measures of disease activity in patients enrolled in the AMPLE (Abatacept Versus Adalimumab Comparison in Biologic-Naive RA Subjects with Background Methotrexate) trial. METHODS In the AMPLE trial, patients with active rheumatoid arthritis (RA) who were naive to biologic agents an...

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