A 54-year-old woman was seen due to weakness and gait difficulty. Physical examination revealed spasticity (Ashworth 2–3), weakness (3/5), hyperactive deep tendon reflexes on the right side, and facial asymmetry. MRI of the brain was consistent with Dyke-Davidoff-Masson Syndrome (DDMS) (figure). DDMS ensues due to an insult to the developing brain, characterized by cerebral hemiatrophy, contral...

A previously well young Filipino boy presented with prolonged recurrent left focal to bilateral seizure. He was born of a non-consanguineous marriage, home-delivered vaginally, full term no perinatal complications. had normal growth and developmental milestones until at the age 7 months when he developed febrile status epilepticus. Since then, residual hemiplegia, dysarthria, cognitive delay se...

Cerebral hemiatrophy Diagnosed Homolateral hypertrophy Dyke – Davidoff – Masson Syndrome (DDMS), also called as cerebral hemiatrophy, is a rare clinical condition characterized by seizures, facial asymmetry, contralateral spastic hemiplegia or hemiparesis, with learning difficulties. It is commonly diagnosed in presence of associated radiologic findings which include cerebral hemiatrophy with h...

A 21-year-old man presented with complex partial status epilepticus. His past medical history was marked by epilepsy and his examination disclosed atrophy of the right limbs and hemiparesis in the same side of the body. A brain CT scan showed atrophy of the entire left hemisphere, with prominent sulci, enlargement of the lateral ventricle and overdevelopment of the frontal sinuses on the left s...

A diagnosis of central hypothyroidism (CH) can be missed easily or delayed without a high index of suspicion due to normal or slightly altered thyroid stimulating hormone (TSH) levels during the initial screening test for thyroid dysfunction. A correct diagnosis of CH is very important for safely treating patients. Specifically, doctors must ensure a proper evaluation of combined adrenal insuff...