Sensory processing is impaired in focal hand dystonia (FHD), with most previous studies having evaluated only the symptomatic limb. The purpose of this study was to establish whether the sensory system is affected in other types of dystonias and whether the contralateral hand is also involved in FHD. We used a spatial acuity measure (Johnson-Van Boven-Phillips domes) to evaluate sensory spatial...

Primary dystonia is thought to be a disorder of the basal ganglia because the symptoms resemble those of patients who have anatomical lesions in the same regions of the brain (secondary dystonia). However, these two groups of patients respond differently to therapy suggesting differences in pathophysiological mechanisms. Pathophysiological deficits in primary dystonia are well characterized and...

background : deep brain stimulation (dbs) of the globuspallidusinternus (gpi) is recommended as a promising technique for the management of the primary generalized dystonia (pgd) with dyt1 gene mutation. we present the first report of dbs results in iranian patients with dyt1 positive pgd.   methods : nine patients who suffered from severely disabling dyt1 positive pgd consecutively were recrui...

objective: the purpose of this study was to evaluate the effect of attachment-based interventions on females suffering from eating related disorders. the study method was experimental with a pretest-posttest control group. the study sample included 32 elementary school female students with eating disorders, obesity problems, and attachment disorders. sampling method was purposive.  methods: aft...

Dystonia is a hyperkinetic movement disorder characterized by sustained muscle contractions that produce repetitive movements and abnormal postures. Specific information on the prevalence of dystonia has been difficult to establish because the existing epidemiological studies of the condition have adopted different methodologies for case ascertainment, resulting in widely differing reported pre...

BACKGROUND To our knowledge, no study has assessed the validity of family history data provided by probands with adult-onset dystonia. OBJECTIVE To measure the sensitivity and specificity of interviewing patients with primary adult-onset dystonia as a method for obtaining information on dystonia in first-degree relatives. PARTICIPANTS Seventy probands with primary adult-onset dystonia were ...

Focal dystonia is the most common form of primary dystonia characterized by involuntary twisting, abnormal postures and repetitive movements in a specific body part. Musician’s dystonia (MD) is a type of focal task-specific dystonia that presents with loss of voluntary motor control of extensively trained movements when a musician is playing his instrument. The pathophysiology of focal dystonia...

Dystonia is defined as a neurological syndrome characterized by involuntary sustained or intermittent muscle contractions causing twisting, often repetitive movements, and postures. Paroxysmal dyskinesias are episodic movement disorders encompassing dystonia, chorea, athetosis, and ballism in conscious individuals. Several decades of research have enhanced the understanding of the etiology of h...

Muscle ultrasound (MUS) is increasingly used by neurologists, neuropediatricians, neurosurgeons, specialized radiologists and anaesthesiologists for the imaging-supported diagnosis of neuromuscular disorders. Especially, MUS highly sensitive in detecting fasciculations motor neuron diseases, revealing intensive care unit acquired weakness. Hereditary inflammatory myopathies are associated with ...