A lattice QCD calculation of the proton matrix element of the flavor singlet axial-vector current is reported. Both the connected and disconnected contributions are calculated, for the latter employing the variant method of wall source without gauge fixing. From simulations in quenched QCD with the Wilson quark action on a 163 × 20 lattice at β = 5.7 (the lattice spacing a ≈ 0.14fm), we find ∆Σ...

objective: breast cancer is the most common cancer in iranian women. breast tumors are classified based on the estrogen receptor alpha (erα) expression status into er negative and er positive tumors. er negative tumors tend to have worse prognosis and less likely to respond to endocrine therapy. aberrant methylation of gene promoter is one of the mechanisms for gene silencing in breast tumors. ...

Background: Histone deacetylation of tumor suppressor genes such as estrogen receptor alpha (ERα) can induce cancer, which is reversible by epi-drugs such as valproic acid (VPA). The previous result indicated that tamoxifen (TAM) induced apoptosis in hepatocellular carcinoma (HCC). This study was designed to assess the apoptotic and antiproliferative effects of VPA and TAM and also the ef...