At present, genetically modified rats have not been generated from ES cells because stable ES cells and a suitable injection method are not available. To monitor the pluripotency of rat ES cells, we generated Oct4-Venus transgenic (Tg) rats via a conventional method, in which Venus is expressed by the Oct4 promoter/enhancer. This monitoring system enabled us to define a significant condition of...

BACKGROUND Trichinella spiralis infection induces protective immunity against re-infection in animal models. Identification of the antigens eliciting acquired immunity during infection is important for vaccine development against Trichinella infection and immunodiagnosis. METHODS AND FINDINGS The T. spiralis adult cDNA library was immunoscreened with sera from pigs experimentally infected wit...

Fossil energy markets have always been known as strategic and important markets. They have a significant impact on the macro economy and financial markets of the world. The nature of these markets are accompanied by sudden shocks and volatility in the prices. Therefore, they must be controlled and forecasted by using appropriate tools. This paper adopts the Generalized Auto Regressive Condition...

The discovery of mouse embryonic stem (ES) cells >20 years ago represented a major advance in biology and experimental medicine, as it enabled the routine manipulation of the mouse genome. Along with the capacity to induce genetic modifications, ES cells provided the basis for establishing an in vitro model of early mammalian development and represented a putative new source of differentiated c...

To date there has been little academic research exploring the theoretical reasons that motivate organizations to adopt Enterprise Systems (ES). By employing Transaction Costs Economics (TCE) and Institutional theory, this research project intends to provide a theoretical foundation to better explain the extent of ES adoption within companies. TCE, Institutional Theory, and combined models are d...

The importance of Expert Systems (ES) as a powerful business tool has become widely recognized in industry. That in turn has led to a major increase in ES development activities and has exacerbated the need to manage these activities for more efficient use of development resources. An important component for effectively managing ES development is an Expert System Development Life Cycle (ESDLC)....

Background: There are various methods to read out responses of a polymer-gel dosimeter, among which the Magnetic Resonance Imaging (MRI) technique is the most common one. Optimizing imaging protocols can have significant effect on the sensitivity and the dose resolution of polymer gel dosimeters. This study has investigated the effects of the number of echoes (NOE) and the echo time spacing (ES...