The search for new markers of high productivity sheep and the introduction evaluation selection methods these indicators is an urgent direction in breeding Russian sheep. material research was results assessment exterior, live weight Romanov Genetic studies were carried out using tissue samples (ear plucking). Polymorphism growth hormone gene evaluated by restriction fragment length polymorphis...

As environmental factors are important in the development of asthma, genetic factors could have a critical role in the expression of the disease. Hence, we carried out a systematic review to assess the susceptible genes for asthma in Iranian population. We conducted a literature search by using the electronic database PubMed, Biological Abstracts Web of Science, Current Contents Connect, Cinahl...

background: henoch-schönlein purpura (hsp) is an lga mediated small vessel systemic vasculitis disease in children. the etiology and pathogenesis of hsp disease remain unknown. however, environmental and genetic risk factors could play important roles in susceptibility to hsp disease. in this study we investigated the association of 5՛-untranslated region polymorphism (-634g/c) of vegf gene wit...

calpastatin (cast) is a specific inhibiter of calpains, playing a role in meat tenderization and myogenesis. in the present study, the polymorphism of the cast gene of makoei sheep was investigated by polymerase chain reaction and single strand conformation polymorphism technique (pcr–sscp). genomic dna was extracted from whole blood samples collected from 100 sheep. a 622 bp cast exon 1 segmen...

BACKGROUND Multiple sclerosis (MS) is an immune-mediated disease of polygenic etiology. Tumor necrosis factor-α (TNF-α) microsatellite as a proinflammatory cytokine is believed to play an important role in the etiology of this disease. OBJECTIVES The aim of this study was to investigate the association of TNF-α microsatellite sequence variation in patients with MS and its risk factor in the s...

introduction : pemphigus vulgaris (pv) is a relatively rare autoimmune disease characterized by blistering of the skin and mucosa. the main objective of this study was to investigate the possible association between the 5-httlpr polymorphism and pv in iranian patients. for this, 112 pv and 100 controls were enrolled in this study. materials and methods : in this case-control study, genomic dna ...

Background: Myasthenia gravis (MG) is the most common disorder of neuromuscular junction in which autoantibodies develop against nicotinic acetylcholine receptor for unknown reasons. The association of immunomodulator genes with different autoimmune disease has been studied in recent years. Objective: The aim of this study was to investigate correlation between a genetic variation in Stromal Ce...

In this study, POU1F1 gene polymorphism was detected in five sheep populations (large-tailed Han, small-tailed Han, Yuxi fat-tailed, Lanzhou large-tailed, and Mongolian sheep), using DNA pooling and sequencing, to provide theoretical basis for the breeding of excellent sheep varieties. Three single-nucleotide polymorphism (SNP) loci of POU1F1 gene were detected in five sheep populations, namely...