نتایج جستجو برای: gastric cancers
تعداد نتایج: 192273 فیلتر نتایج به سال:
Early detection of gastric cancers saves lives, but remains a diagnostic challenge. In this study, we aimed to identify cell-surface biomarkers of early gastric cancer. We hypothesized that a subset of plasma membrane proteins induced by the Helicobacter pylori oncoprotein CagA will be retained in early gastric cancers through non-oncogene addiction. An inducible system for expression of CagA w...
Background and purpose: Angiogenesis provides proper nutrition and helps to the development and spread of cancer cells. Cancer stem cells are a rare population of tumor cells responsible for initiation, spreading and growth of cancer. Angiogenesis occurs more in cancer stem cells compared with other cancer cells. Ibuprofen, as a member of nonsteroidal anti-inflammatory drugs (NSAIDs) group is u...
aim : the present study aimed to evaluate the prevalence of positive family history of these cancers in a large population-based sample of tehran province, capital of iran. background : upper gastrointestinal (ugi) cancers (gastric and esophagus cancer) constitute a major health problem worldwide. a family history of cancer can increase the risk for developing cancer and recognized as one of th...
INTRODUCTION Lung and gastric cancers are the first and second leading causes of death from cancer worldwide, and are especially prevalent in Eastern Asia. Relatively few reports are available in relation to the treatment and outcome of synchronous lung and gastric cancers, although there are increasing numbers of patients with these cancers. Efforts to develop more effective drugs for the trea...
BACKGROUND Helicobacter pylori infection potently induces methylation of CpG islands in gastric mucosae, which is considered to decrease to a certain level after active H. pylori infection discontinues. Noncancerous gastric mucosae of H. pylori-negative cases with a gastric cancer had higher methylation levels than those of H. pylori-negative healthy individuals. Here, using cases with multiple...
BACKGROUND The fall in the incidence of esophageal squamous cell cancer and noncardia gastric cancers in western countries parallels a concomitant rise in the incidence of gastric cardia cancer and distal adenocarcinoma of the esophagus. We aimed to investigate the incidence trend of different gastric and esophageal cancers in Kerman, southeast Iran. METHODS The information of all newly diagn...
Infection-associated cancers account for a large proportion of human cancers, and gastric cancer, the vast majority of which is associated with Helicobacter pylori infection, is a typical example of such cancers. Epigenetic alterations are known to occur frequently in gastric cancers, and H. pylori infection has now been shown to induce aberrant DNA methylation in gastric mucosae. Accumulation ...
BACKGROUND Carbonic anhydrase IX (MN/Ca9) catalyses the reversible metabolism of carbon dioxide to carbonic acid and has also been linked to malignant transformation and hypoxia in various cancers. AIMS To assess the expression and biological role of Ca9 in gastric cancer. METHODS Using gastric cancer cell lines and tissues, we studied expression of Ca9 by western blot analysis, immunohisto...
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