purpose: to compare the prevalence of glaucoma among peptic ulcer patients with or without helicobacter pylori infection. methods: among 352 patients with an indication of gasterointestinal endoscopy for peptic problems, 120 patients in 18-88 years of age were included for evaluation of glaucoma. according to the results of histopathologic and urease test, they were divided into two groups: hel...

BACKGROUND Epidermal growth factor (EGF) and transforming growth factor-alpha (TGF alpha) are potent gastric acid inhibitors and stimuli of mucosal growth and protection but their involvement in Helicobacter pylori associated duodenal ulcer has been little examined. AIM To assess gastric acid secretion, plasma gastrin concentrations, mucosal content of EGF and TGF alpha, and mucosal expressio...

Non-steroidal anti-inflammatory drugs cause gastric ulceration through a number of mechanisms including inhibition of PG synthesis, generation of reactive oxygen species (ROS) and induction of apoptosis. Recently, matrix metalloproteinases (MMP) have been suggested to play a crucial role in these mechanisms. The present study investigated the protective effect of anthocyanins isolated from blac...

The roots of Dipsacus asper (DA) have been used as a tonic and analgesic agent in traditional Chinese medicine for the treatment of osteoporosis, low back pain, knee pain, and as an anti-inflammatory agent. Few studies have reported pharmacological gastric activities. In this study, we investigated the effects of dipsacussaponin C (DSC) and 70% ethanol and water extracts of DA on gastritis and ...

background: cd1d presents glycolipid antigens to invariant natural killer t (inkt) cells. the role of cd1d in the development of peptic ulcer and gastric cancer has not been revealed, yet. objective: to clarify the expression of alternatively spliced variants of cd1d in peptic ulcer and gastric cancer. methods: patients with dyspepsia were selected and divided into three groups of non-ulcer dys...

peptic ulcer is a very common disorder in horse race and foals. in the present research possible relationship between gastric ulcer and the prevalence of cardiac arrhythmia were studied in two different horse race. in this respect, 13 caspian miniature horses and 8 arab horses were studied. gastric ulcers and cardiac arrhythmias were diagnosed in 13 horses (62%) and 12 (57%) out of 211 horses, ...

background: basic fibroblast growth factor (bfgf) is a glycoprotein with stimulating ability of angiogenesis. in addition, bfgf plays an important role in wound healing process in some tissues for example gastrointestinal tract, but its ability for discrimination of various stages of wound severity in these diseases was not reported. therefore, we aimed to determine the bfgf levels in gastric u...

Simvastatin appeared to have additional benefits beyond their lipid lowering effects, which has led to interest in the use of this class of drugs outside the field of cardiovascular disease. Aim: This study aimed to investigate the possible gastroprotective effect of simvastatin against both indomethacin and cold restraint stress (CRS) induced gastric ulcers in rats and to study its effect on g...

aqueous (hydrophilic) and chloroform (lipophilic) extracts of nine medicinal plants currently used in traditional medicine, in egypt, to treat some gastrointestinal tract (git) disorders were tested for their gastro-protective effect against the incidence of peptic ulcer. indomethacin-induced ulcer in a rat model was used for this testing. mentha microphylla, brassica oleracea capitata (cabbage...