The linkage of the major histocompatibility complex (MHC) and the growth and reproduction complex (Grc) in the rat was studied in an F2 hybrid population generated from female BIL/1 (RT1l-Grc) and male YO (RT1u-Grc+) animals: 1.722 offspring were born, and 1,568 were weaned and studied. The body weights of the offspring segregated with the RT1 haplotype of the MHC, and the RT1l homozygotes were...

The glyoxylate regeneration cycle (GRC) operates in serine cycle methylotrophs to effect the net conversion of acetyl coenzyme A to glyoxylate. Mutants have been generated in several genes involved in the GRC, and phenotypic analysis has been carried out to clarify their role in this cycle.

The exact mechanism by which carcinogens and tumor promoters act on the glucocorticoid receptor system in vivo is not known. Based on earlier studies that sulfhydryl-reducing agents stabilize glucocorticoid receptor binding in vitro, some workers have postulated that endogenous reducing factors may be important for glucocorticoid receptor function in vivo. To test whether glutathione (GSH) may ...

What is granular computing(GrC)? It is a shifting paradigm. Let us start with a few words about how the term was coined. In the academic year 1996-97, when Lin (this section editor) took his sabbatical leave at UC-Berkeley, Zadeh suggested granular mathematics (GrM) to be his research area. To limit the scope, Lin proposed the term granular computing [14]. What was GrC then? Zadeh had outlined ...

Gene regulatory cascades (GRCs) are common motifs in cellular molecular networks. A given logical function in these cascades, such as the repression of the activity of a transcription factor, can be implemented by a number of different regulatory mechanisms. The potential consequences for the dynamic performance of the GRC of choosing one mechanism over another have not been analysed systematic...

Today, enterprises have reached to understanding that Information Technology (IT) is more than just a technical issue. Disciplines such as IT governance, (IT) risk management and (IT) compliance have been established to steer it. Though, there has been some improvements, these domains are usually focused separately in silos, which raises a problem of performance and efficiency, where less busin...