Vicinal aminoalcohols are widespread structural motifs in bioactive molecules. We report the development of a new dioxazolone reagent containing p-nitrophenyldifluoromethyl group, which 1. displays good safety profile; 2. shows remarkably high reactivity oxime-directed iridium(III)-catalyzed amidation unactivated C(sp3)−H bonds; 3. leads to amide products can be hydrolyzed under mild conditions...

In the title compound, C(14)H(17)N(2)O(4)P·CH(3)OH, the planes of the pyridinium-2-ylamino and 2-hydroxy-phenyl groups form a dihedral angle of 75.6 (1)°, with the pyridinium NH group and the 2-hydroxy-phenyl OH group pointing in opposite directions. Three intra-molecular hydrogen bonds are observed. Two phospho-nate and two methanol mol-ecules are connected by O-H⋯O hydrogen bonds as a centros...

In the crystal structure of the title compound, C(11)H(9)ClN(4)O(3), pairs of N-H⋯N(imidazole) hydrogen bonds connect the mol-ecules into centrosymmetric dimers, which are further connected by N-H⋯O(carbamo-yl) hydrogen bonds into C(4) chains along [010]. Inter-play of these two kinds of hydrogen bonds connect the mol-ecules into layers perpendicular to [101]. The imidazole [maximum deviation 0...

The asymmetric unit of the title compound, C(11)H(13)ClN(2)OS, contains two independent mol-ecules. Both mol-ecules maintain a trans-cis configuration with respect to the position of the carbonyl group and the benzene ring against the thione group across the C-N bonds. The mol-ecules are stabilized by intra-molecular N-H⋯O hydrogen bonds. In the crystal, the mol-ecules are linked by inter-molec...

The title compound, C16H14O6, was recrystallized under solvothermal conditions. The mol-ecules are located on inversion centres, with one complete mol-ecule generated from the asymmetric unit by inversion. There are intra-molecular O-H⋯O hydrogen bonds involving the carb-oxy-lic acid group and the O atom of the adjacent meth-oxy group. In the crystal, mol-ecules are linked via O-H⋯O hydrogen bo...

Sociality has evolved in many animal taxa, but primates are unusual because they establish highly differentiated bonds with other group members. Such bonds are particularly pronounced among females in species like baboons, with female philopatry and male dispersal. These relationships seem to confer a number of short-term benefits on females, and sociality enhances infant survival in some popul...

The title compound, C18H30N2O5S, was synthesized by the reaction of tert-butyl 2-(iso-butyl-amino)-ethyl-carbamate with p-meth-oxy-phenyl-sulfonyl chloride. In the mol-ecule, two intra-molecular C-H⋯O hydrogen bonds are observed. In the crystal, mol-ecules are linked by N-H⋯O hydrogen bonds involving the imino group N atom and the ester group O atom into chains running parallel to the b axis. T...

     The effects of substituents on the symmetry and the nature of halogen bonds in [N∙∙∙X∙∙∙N]+-type systems are presented for the YC5H4N∙∙∙X∙∙∙NC5H5 (Y = NO2, CN, H, CH3, OCH3, OH, NH2, X = Cl, Br, I) complexes. Some structural parameters, energy data and electronic properties were explored with...