although gastrointestinal bleeding is common, hemobilia due to the rupture of hepatic artery pseudoaneurysm is uncommon. we report a case of hemobilia which was successfully treated via angiography.

AMD chronic administration induces hepatic lipid accumulation by several mechanisms, including induction of ER stress, impairment β-oxidation, and inhibition triacylglycerol secretion. Our study shows that repetitive treatment not only stress but also adipose tissue lipolysis free fatty acids enrichment palmitate in the total lipids. Understanding toxicity mechanisms would help devise ways to l...

Near-infrared spectroscopy (NIRS) is a novel method for the measurement of tissue oxygenation and may have a role in monitoring liver oxygenation and viability. The aim of this study is to validate the application of NIRS for monitoring hepatic tissue oxygenation. Large Landrace pigs (n = 12) underwent laparotomy and liver exposure. Total hepatic blood flow (THBF) was measured by the Transonic ...

Hepatic ischemia-reperfusion (I/R) is a common phenomenon during liver surgery, transplantation, infection and trauma which results in damage and necrosis of the hepatic tissue through different pathways. Mechanisms involved in I/R damage are very intricate and cover several aspects. Several factors are involved in I/R-induced damages; briefly, decrease in sinusoidal perfusion and ATP generatio...

Objective(s): Our present study sought to evaluate hepatoprotective and antioxidant effects of methanol extract of Azolla microphylla phytochemically synthesized gold nanoparticles (GNaP) in acetaminophen (APAP) - induced hepatotoxicity of fresh water common carp fish.Materials and Methods: GNaP were prepared by green synthesis method using methanol extract of Azolla microphylla.  Twenty four f...

objective(s): particularly in developing countries, selenium and/or iodine deficiencies are encountered and use of pesticides in agriculture are not well-controlled. fenvalerate is a pyrethroid insectide used in agriculture and has applications against a wide range of pests. this study was designed to evaluate the effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzyme act...