An elastic finite element analysis was conducted to evaluate the stress distribution in the initiation zone of the adhesive rupture during the 3-point bending test. This test is used to measure the adherence between a polyepoxy adhesive and aluminum alloy with different surface treatments. The purpose is to compare, in the high stress concentration areas, the stress fields calculated using fini...

Motivation Translation initiation is a key step in the regulation of gene expression. In addition to the annotated translation initiation sites (TISs), the translation process may also start at multiple alternative TISs (including both AUG and non-AUG codons), which makes it challenging to predict TISs and study the underlying regulatory mechanisms. Meanwhile, the advent of several high-through...

Genetic predisposition without doubt is one of the risk factors cancer initiation. It known that single nucleotide polymorphisms (SNP) genes maintain genome stability, including SNP DNA repair, may contribute to initiation carcinogenesis. Single-nucleotide support repair genes, can Polymorphism excision gene OGG1 causes interest leading scientific groups from various countries. assumed there re...

Present study deals with the prediction of crack initiation angle for mixed mode (I/II) fracture using finite element techniques and J-Integral based approach. The FE code ANSYS is used to estimate the stress intensity factor numerically. The estimated values of SIF were incorporated into six different crack initiation angle criteria to predict the crack initiation angle. Single edge crack spec...

This paper experimentally investigates the fatigue damage evolution in pre-corroded aluminum alloy (AA) 7075-T7651 via digital image correlation (DIC) and scanning electron microscopy (SEM). Three stages of including accumulation, macro-crack initiation propagation are identified described combined analysis severity curves strain maps. The micro-cracking characteristics dominant fracture region...

introduction: one of the main complications of hemodialysis in patients with chronic renal failure is hypoxemia which is related to several factors including the type of filter. the aim of this study was to evaluate the hypoxemia levels in patients undergoing hemodialysis with focus on the type of filter. methods: in a crossover clinical trial, 29 patients from emodialysis ward of fatemieh hosp...

abstract in order to study the effects of irrigation regimes on physiological traits, yield and water use efficiency of potato (solanum tuberosum l.) in mashhad weather condition, an experiment was conducted in 2009 at research field of the college of agriculture, ferdowsi university of mashhad, using factorial experiment based on randomized complete blocks design with 3 replications. experimen...

Viral DNA packaging motors are among the most powerful molecular motors known. A variety of structural, biochemical, and single-molecule biophysical approaches have been used to understand their mechanochemistry. However, packaging initiation has been difficult to analyze because of its transient and highly dynamic nature. Here, we developed a single-molecule fluorescence assay that allowed vis...

We describe the results of a genome-wide analysis of human cells that suggests that most protein-coding genes, including most genes thought to be transcriptionally inactive, experience transcription initiation. We found that nucleosomes with H3K4me3 and H3K9,14Ac modifications, together with RNA polymerase II, occupy the promoters of most protein-coding genes in human embryonic stem cells. Only...

SUMMARY Alternative translational initiation is an important cellular mechanism contributing to the diversity of protein products and functions. We develop a database that provides a comprehensive collection of alternative translational initiation events. The purpose of this alternative translational initiation database (ATID) is to facilitate the systematic study of alternative translational i...