Objectives. The purpose of this study is to investigate the relationship between plasma endocannabinoids and insulin resistance (IR) in patients with obstructive sleep apnea (OSA). Methods. A population of 64 with OSA and 24 control subjects was recruited. Body mass index (BMI), waist circumference, lipids, blood glucose and insulin, homeostasis model of assessment for insulin resistance index ...

BACKGROUND Polycystic ovary syndrome (PCOS), a common endocrine disorder, is associated with infertility, menstrual dysfunction, hirsutism and frequent miscarriages. Insulin resistance, as a major cause of PCOS, represents a disorder with increase in inflammatory markers and risk of type 2 diabetes. We aimed to investigate whether inflammatory markers, including C-reactive protein and C3 (Compl...

OBJECTIVE To test the association between cognitive impairment, with and without subcortical features, and insulin resistance in an elderly community-dwelling population. DESIGN Cross-sectional wave of an epidemiologic longitudinal study (InCHIANTI). PARTICIPANTS A total of 523 people, aged 70 to 90 years without diabetes mellitus or hyperglycemia, from the InCHIANTI cohort were included in...

Objective: Adiponectin (an insulin sensitizing protein) and zinc have insulin like effect. This study was conducted to assess the effect of zinc supplementation on serum adiponectin and insulin resistance in first degree relatives of diabetic patients. Materials and Methods: This study was a randomized clinical trial performed on 58 first degree relatives of diabetic patients with normal gluco...

Objective: The overweight-related health problems among adolescents are obvious. Resistance training is recognized as a safe and efficacious exercise modality to have health-promoting effects in overweight adolescents. This study aimed to assess the efficacy of circuit resistance training (CRT) in improving inflammatory status, insulin resistance and body composition in overweight male adolesce...

BACKGROUND Insulin resistance is of utmost importance as an underlying mechanism for increased risk of cardiovascular disease (CVD). We assessed the association between Homeostatic Model Assessment (HOMA-IR) and two surrogate subclinical atherosclerosis markers (SCA) among individuals with and without type 2 diabetes (DM), those who did not have any clinical presentation of the CVD. METHODS I...

OBJECTIVES We investigated the relationship between insulin resistance reflected by homeostasis model assessment (HOMA-IR) index and serum HbA1c levels of obese children. MATERIAL AND METHODS This study included 70 obese and 60 normal weight healthy children between the ages of 3 and 15. Anthropometric measures and biochemical tests (fasting glucose, fasting insulin, HbA1c) were performed on ...

OBJECTIVE Plasma interleukin-18 (IL-18) has been reported to be associated with homeostasis model assessment of insulin resistance (HOMA-IR). It also has been described as one of the factors that, in addition to insulin resistance, may also contribute to atherosclerosis. Parameters of systemic inflammation are also significantly associated with circulating IL-18. Our objective was to investigat...

BACKGROUND Upper body fat distribution is associated with the early development of insulin resistance in obese children and adolescents. OBJECTIVE To determine if an android to gynoid fat ratio is associated with the severity of insulin resistance in obese children and adolescents, whereas peripheral subcutaneous fat may have a protective effect against insulin resistance. SETTING The pedia...