interleukin 28b

OBJECTIVES The favorable CC genotype at rs12979860 upstream of the interleukin (IL)-28B gene is correlated with a greater post-treatment sustained virologic response rate in chronic hepatitis C infected patients. We report on our validation of a clinical genotyping assay for rs12979860 polymorphisms in the IL28B locus. DESIGN AND METHODS The rs12979860 genotype was determined using a TaqMan® ...

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Elevated on-treatment levels of serum IFN-gamma is associated with treatment failure of peginterferon plus ribavirin therapy for chronic hepatitis C

2016

Ming-Ying Lu Ching-I Huang Chia-Yen Dai Shu-Chi Wang Ming-Yen Hsieh Meng-Hsuan Hsieh Po-Cheng Liang Yi-Hung Lin Nai-Jen Hou Ming-Lun Yeh Chung-Feng Huang Zu-Yau Lin Shinn-Cherng Chen Jee-Fu Huang Wan-Long Chuang Ming-Lung Yu

Chronic hepatitis C virus (HCV) infection had been associated with cytokine imbalance. Cytokine dynamics in response to peginterferon/ribavirin therapy have an impact on the treatment efficacy for HCV patients. Ninety-two treatment-naive chronic hepatitis C patients were treated with 24 or 48 weeks of peginterferon/ribavirin therapy according to their viral genotypes. Sustained virologic respon...

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Interleukin 28B Polymorphisms and Hepatitis C—Translating the Association into Clinical Decision Making

Journal: :Journal of Clinical and Experimental Hepatology 2011

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ROLE OF SERUM INTERLEUKIN – 10 AND INTERLEUKIN -28B GENE POLYMORPHISMS IN PREDICTING TREATMENT RESPONSE OF HEPATITIS C PATIENTS

Journal: :Zagazig University Medical Journal 2017

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Biliary strictures after liver transplantation: Role of interleukin 28B genotypes in cyclosporine treated

Journal: :International Journal of Surgery 2014

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