J . H . LEVY ,* W. AGENO,† N. C . CHAN,‡ M. CROWTHER ,§ P . VERHAMME ¶ and J . I . WE ITZ ,§ FOR THE SUBCOMMITTEE ON CONTROL OF ANT ICOAGULAT ION *Duke University School of Medicine, Durham, NC, USA; †University of Insubria, Varese, Italy; ‡Monash University, Clayton, Vic., Australia; §McMaster University and the Thrombosis and Atherosclerosis Research Institute, Hamilton, ON, Canada; and ¶Univ...

Background and Purpose: Candida albicans is the most common causative agent of candidiasis. Candidiasis management is dependent on the immune status of the host, severity of disease, and the choice of antifungal drug. Antifungals, specifically triazoles, are widely administered for the treatment of invasive fungal infections. Herein, we aimed to evaluate the in vitro susceptibility of C. alb...

To improve sustainability and reduce costs, interest in using limestone powder (LP) ultra-high performance concrete (UHPC) has been increasing recent years. Incorporating LP changes packing, characteristics of C–S–H pore structure interfacial transition zone (ITZ) matrix by physical chemical effects. However, the influences replacement on mechanical properties UHPC, from micromechanics to macro...

Flexural toppling failure is a common mode of natural and artificial rock slopes, which has caused serious damage to human life property. In this work, an advanced numerical method called the Universal Distinct Element Code (UDEC) was used study mechanism flexural failure. total, more than twenty slope models were built analyzed. Two new parameters (displacement discontinuity transition coeffic...

For a number of years a new scientiJc unity has been developing frotn a synthesis itz which chemistry and physics have become closely lirlked with biology. On the biological side cytologists are concerned with what happens to the nucleo-proteins and the nucleic acids present in plant and animal cells. These compounds are of great interest to biochemists atld biophysicists, and during I953 impor...

A computational homogenization technique for modeling diffusion in concrete is introduced with emphasis on the influence of aggregate content and variability. The highly heterogeneous material investigated different scales by combining Variationally Consistent Homogenization numerical microstructures analytical techniques accounting lower, unresolved, length scales. structure consists cement pa...

Penicillium chrysogenum was isolated from three subsequent cerebrospinal fluid (CSF) specimens of a 73-year-old male patient without immunological compromise. The isolated was tested against five antifungal agents according to the NCCLS M38-P macrodilution method. MICs were determined as follows: amphotericin B (AMB), 2 microg ml(-1); fluconazole (FLZ), 8 microg ml(-1); itraconazole (ITZ), 1 mi...

Using meso-structural representations of concrete, with aggregates dispersed in mortar, has become a standard approach for damage and fracture analysis. However, there is no full agreement on appropriate modelling different phases the inclusion interfacial transition zones (ITZ). This work explores mortar ITZ formulations by comparison own experiments demonstrates that optimal strategy balancin...