PURPOSE To investigate whether microRNA (MIR)-184 mutations make a substantial contribution to keratoconus (KCN) among affected Iranian patients. METHODS A total of 47 Iranian KCN patients, diagnosed based on family history, clinical examinations using slit lamp biomicroscopy, refraction and corneal topography were enrolled in this study. The pri-miR-184 encoding gene obtained from the DNAs o...

The addition of androstenedione and NADPH to human placental microsomes results in a marked increase in the rate of 0 2 and NADPH utilization concomitant with estrogen formation. Initially, 5 to 12 moles of O2 and an equivalent amount of NADPH are consumed per mole of estrogen formed, the ratio varying from one microsomal preparation to another. In the presence, however, of 10 to 20 mM KCN, 3 m...

The half-time for oxidation of cytochrome b(557) in mitochondria from etiolated mung bean (Phaseolus aureus) hypocotyls is 5.8 milliseconds at 24 Celsius in the absence or presence of 0.3 mm KCN, when the oxidation is carried out by injecting a small amount of oxygenated medium into a suspension of mitochondria made anaerobic in the presence of succinate plus malonate. Since oxygen is consumed ...

Bacterial aerobic respiration has recently been related to the outcome of antibiotic treatment in experimental studies, but clinical relevance levels bacterial remains be evidenced. Therefore, we hypothesized that is lower sputum from people with cystic fibrosis (pwCF) and chronic lung infection, where cure difficult rare, than patients acute respiratory tract infections (aLRTI), frequent. Oxyg...

purpose: to investigate the association between acute corneal hydrops in patients with keratoconus (kcn) and mitral valve prolapse (mvp). methods: this case-control study included kcn patients with corneal hydrops who were referred to labbafinejad medical center or a collaborating private clinic from march 2006 to march 2008 as the case group. the control group included age- and sex-matched ind...

Corneal cross-linking (CXL) is an option that in the last decade has demonstrated its efficacy and safety in halting the progression of keratoconus (KCN) and other corneal ectasias. Its indication has been extended beyond the classic definition that required evidence of KCN progression, especially in the presence of some risk factors for a possible progression (particularly the younger age). Ho...