case presentation a 28-year old chinese female was treated with carbimazole (cmz) for graves’ disease with hyperthyroidism. two weeks later, she developed myalgia and proximal muscle weakness. investigations showed evidence of myopathy. cmz was stopped and rapid improvement of clinical condition and biochemical parameters ensued. conclusions rapid decrement of thyroid hormone level is recognize...

myocardial infarction (mi) is one of the most important health burdens worldwide. aspirin as an non- steroid anti—inflammatory drug, has been proven to be a protective factor to decrease the incidence, however its effect of mi size is still unknown. we designed this study to compare the biomarkers after mi in patients with and without aspirin intake. 378 patients were enrolled and the results s...

conclusions in conclusion, mma official and simulated matches induce similar high intensity glycolytic demands and minimal changes to biochemical markers of muscle damage immediately following the fights. glycolytic availability prior to the fights was raised exclusively in response to official matches. objectives the main objective of this study was to compare biochemical responses to sparring...

background: the wnt/β- the wnt/β-catenin signaling pathway is involved in many developmental processes in both fetal and adult life; its abnormalities can lead to disorders including several types of cancers and malfunction of specific cells and tissues in both animals and humans. its role in reproductive processes has been proven. objective: this study was designed to evaluate the expression o...

introduction: the use of antioxidants before high-intensity training, which leads to the release of free radicals and muscle injuries, can result in reduced damage during exercise. accordingly, in this study, we aimed to evaluate the effect of selenium supplement intake on oxidative stress, following exhaustive aerobic exercise among young physically-active females. methods: in this quasi-exper...

purpose: myocardial infarction is among the most common diagnoses in patients admitted   to hospitals in western countries, and its rapid diagnosis is of utmost importance. this study   was conducted to determine the most sensitive double-marker cardiac isoenzyme of creatinine   kinase, troponin i, and myoglobin for diagnosing acute myocardial infarction.   materials and methods: this was an ob...

we have investigated the effect of theophylline on the kinetics of the catalytic subunit of protein kinase and related factors in lung tissue. the results show that the point of highest concentration of the c subunit of protein kinase which is active in casein phosphorylation is at 3h of incubation time, but in the presence of 100 ilg/ inl and 10µg/ml theophylline, this is shifted to i.s and 2....

introduction: atherosclerosis, hypertension, ischemic diseases, alzheimer’s disease, parkinson disease, cancer and inflammation emerge from imbalance between antioxidant and oxidants. cancer is a most important public health problem in both developed and developing countries. natural antioxidants such as polyphenols are being used for prevention and treatment cancer. polyphenols include phenoli...

Adenylate kinases (ADK) are ubiquitous enzymes that contribute to the homeostasis of adeninenucleotides in living cells. In this study, the cloning of a cDNA encoding an adenylate kinase from the filariaOnchocerca volvulus has been described. Using PCR technique, a 281 bp cDNA fragment encoding part ofan adenylate kinase was isolated from an O. volvulus cDNA library. Use of this fragment as a p...