Background and Objectives: Strenuous exercises have been shown to induce inflammation. However, consumption of products rich in antioxidants such as vitamin C may enhance this effect. The purpose of this study was to assess effects of vitamin C supplementation on C-reactive protein, lactate and blood pressure following resistance exercise in overweight men. Materials and Methods: In a randomiz...

background: lactic acidosis in cardiac surgical patients is a manifestation of systemic inflammation and excess pro-inflammatory cytokine production. this investigation was designed to integrate basic concepts about lactate acidosis with a clinically used of serum lactate in patients under coronary artery bypass surgery (cabg) by on pump method. methods: from august to september 2012, 15 patien...

Choline plays a lipotropic role in lipid metabolism as an essential nutrient. In this study, we investigated the effects of choline (5, 35 and 70 μM) on DNA methylation modifications, mRNA expression of the critical genes and their enzyme activities involved in hepatic lipid metabolism, mitochondrial membrane potential (Δψm) and glutathione peroxidase (GSH-Px) in C3A cells exposed to excessive ...

phase transition from vegetative to reproductive growth is an important character for winter wheat under cold conditions because it decreases the ability of wheat plants to maintain frost tolerance. reproductive development in winter wheat is triggered by fulfillment of vernalization requirements. this study was conducted to determine the inter-relationship between developmental stages and free...

Background: Lactic acidosis in cardiac surgical patients is a manifestation of systemic inflammation and excess pro-inflammatory cytokine production. This investigation was designed to integrate basic concepts about lactate acidosis with a clinically used of serum lactate in patients under coronary artery bypass surgery (CABG) by on pump method. Methods: From August to September 2012, 15 patie...

Blood lactate concentration (BLC) is widely used to guide resuscitation in critically ill patients [1]. Muscular microdialysis has previously been used illustrate the importance of the Na/K pump in hyperlactatemia in septic shock patients [2], with BLC reflecting metabolic changes rather than oxygen debt [3]. Microdialysis has now also been applied to intravascular continuous monitoring [4] (Ei...

Substrate and product inhibition of hydrogen production during sucrose fermentation by the extremely thermophilic bacterium Caldicellulosiruptor saccharolyticus was studied. The inhibition kinetics were analyzed with a noncompetitive, nonlinear inhibition model. Hydrogen was the most severe inhibitor when allowed to accumulate in the culture. Concentrations of 5-10 mM H(2) in the gas phase (ide...

Acid tolerance of the lactic acid bacterium (LAB) is crucially important for production free as a chemical monomer by simplified purification steps. This study conducts both metabolic modification and adaptive evolution approaches on increasing an engineered Pediococcus acidilactici strain. The overexpression genes encoding lactate dehydrogenase, recombinase, chaperone, glutathione ATPase did n...

Exercise induced rhabdomyolysis is a complication of long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) and mitochondrial trifunctional protein (TFP) deficiency that frequently leads to exercise avoidance. Dietary therapy for most subjects includes medium-chain triglyceride (MCT) supplementation but analysis of diet records indicates that the majority of patients consume oral MCT only with brea...

BACKGROUND Intensive care of severe trauma patients focuses on the treatment of haemorrhagic shock. Tissues should be perfused sufficiently with blood and with sufficient oxygen content to ensure adequate tissue oxygen delivery. Tissue metabolism can be monitored by microdialysis, and the lactate/pyruvate ratio (LPR) may be used as a tissue ischemia marker. The aim of this study was to determin...