BACKGROUND Treatment for local glottic cancer recurrences after primary transoral laser microsurgery (TLM) has not been standardized. METHODS In 33 consecutive cases of salvage TLM after laser surgery for early glottic carcinoma failed, we retrospectively considered the potential clinicopathological prognostic factors in univariate statistical setting. RESULTS Patient age <65 years and path...

BACKGROUND Transoral laser microsurgery (TLM) is a mature approach to supraglottic cancer, while transoral robotic surgery (TORS) is emerging. The present study compared these approaches. METHODS The first 10 patients (2002-2005) given TLM were compared with the first 10 (2007-2011) given TORS for cT1-3 cN0-cN2c supraglottic cancer. RESULTS A feeding tube was used in four TLM and seven TORS...

Background:The nucleolinus is a little known cellular structure associated with the nucleolus that was discovered over 150 years ago. Results: It contains a unique set of molecules associated with cell division. Conclusion: Combined with laser microsurgery experiments, the observations suggest a role for the nucleolinus in spindle formation. Significance: The nucleolinus appears to be a tangibl...

Increasing evidence in eukaryotic cells suggests that mechanical forces are essential for building a robust mitotic apparatus and correcting inappropriate chromosome attachments. In this issue, Cojoc et al. (2016. J. Cell Biol., http://dx.doi.org/10.1083/jcb.201506011) use laser microsurgery in vivo to measure and study the viscoelastic properties of kinetochores.

CO2 laser is used to resect or vaporise benign and malignant lesions of the upper aerodigestive tract. This chapter focuses on transoral CO2 laser technique using a micromanipulator attached to an operating microscope. The advantages of using CO2 laser with an operating microscope are microsurgical precision, excellent intraoperative detail, and a dry surgical field; the functional outcomes in ...

INTRODUCTION Transoral laser microsurgery (TLM) represents one of the most effective treatment strategies for Tis-T2 glottic squamous cell carcinomas (SCC). The prognostic influence of close/positive margins is still debated, and the role of narrow band imaging (NBI) in their intraoperative definition is still to be validated on large cohort of patients. This study analyzed the influence of mar...

OBJECTIVE The KTP laser has become commonplace in transoral head and neck surgery. The interactions of this laser with commonly used supplies in transoral surgery have not been formally examined. This study evaluates the effects of the KTP laser on surgical supplies. STUDY DESIGN Experimental study. SETTING The study was conducted in an empty operating room at a university-affiliated medica...

Laser microsurgery is the current gold standard surgical technique for treatment of selected diseases in delicate organs such as larynx. However, operations require large expertise and dexterity, face significant limitations imposed by available technology, requirement direct line sight to field, restricted access, manual control instruments. To change this status quo, European project ?RALP pi...

UNLABELLED Introduction The diode laser has been frequently used in the management of laryngeal disorders. The portability and functional diversity of this tool make it a reasonable alternative to conventional lasers. However, whether diode laser has been applied in transoral laser microsurgery, the ideal parameters, outcomes, and adverse effects remain unclear. Objective The main objective of ...