Introduction: Memantine (MEM) is a noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist clinically used for the treatment of Alzheimer disease (AD) in mild to severe conditions. The present study was conducted to investigate the effects of memantine on the spontaneous firing frequency of CA1 pyramidal neurons in rats caused by an electrical lesion of Nucleus Basalis Magnocellularis (...

  Ancient schwannomas rarely found in the central nervous system and ancient change in an intracranial schwannoma (intracranial portion of the trigeminal nerve) is extremely rare. A seventy-year man presented with headache of 3 months duration and one episode of generalized tonic-clonic seizures. Imaging findings were suggestive of left temporal high grade lesion. During surgery there was well...

A 64-year-old Iranian woman presented with a genital erosive skin lesion that she had noticed from two years ago. On physical examination, a 20 to 25 millimeter purplish lesion was observed on the vulval skin (Figure 1). The indurated lesion showed a small central erosion measuring 3 to 5 mm. Inguinal lymph nodules were not palpable. A skin biopsy specimen was obtained from the eroded les...

ancient schwannomas rarely found in the central nervous system and ancient change in an intracranial schwannoma (intracranial portion of the trigeminal nerve) is extremely rare. a seventy-year man presented with headache of 3 months duration and one episode of generalized tonic-clonic seizures. imaging findings were suggestive of left temporal high grade lesion. during surgery there was well ca...

cemento-ossifying fibroma is a fibro-osseous lesion that has benign neoplastic behavior. we report two cases of cemento-ossifying fibroma (cof) and review the literature in order to study the imaging findings of cof. it is almost unavoidable that diagnosis of fibrous dysplasia from cof will be complicated by the fact that some pathologic features are shared by both lesions. so the final definit...