C3H mice chronically infected with LCM virus were found to be lethally affected by small doses of immunosuppression which caused bone marrow aplasia but had no effect on the amount of virus carried by the mouse. Humoral immune response of SWR/J mice to acute LCM infection was found to be totally suppressed by repeated single doses of 300 R/wk with no alteration in the level of virus carried by ...

BACKGROUND A striking difference in fish consumption and lung cancer mortality (LCM) exists among populations worldwide. This study investigated the relation between fish consumption and LCM at the population level. METHODS Sex-specific LCM data, mostly around 1993 and fish consumption data for 10 periods 1961-1994 in 36 countries were obtained from WHO and FAO, respectively. RESULTS A sign...

The advent of new technologies has enabled deeper insight into processes at subcellular levels, which will ultimately improve diagnostic procedures and patient outcome. Thanks to cell enrichment methods, it is now possible to study cells in their native environment. This has greatly contributed to a rapid growth in several areas, such as gene expression analysis, proteomics, and metabolonomics....

Laser capture microdissection (LCM) of tissue is an established tool in medical research for collection of distinguished cell populations under direct microscopic visualization for molecular analysis. LCM samples have been successfully analyzed in a number of genomic and proteomic downstream molecular applications. However, LCM sample collection and preparation procedure has to be adapted to ea...

PURPOSE Defining the tolerability and safety profile of recently marketed antiepileptic drugs, such as lacosamide (LCM), is a prerequisite for their optimal utilization in clinical practice. We aimed to identify any adverse event (AE) associated with LCM treatment by conducting a systematic review and meta-analysis of all available randomized controlled trials (RCTs). We also evaluated the asso...

Recently, work in this group has focused on the lateral cosine modulation method (LCM) which can be used for next-generation ultrasound (US) echo imaging and tissue displacement vector/strain tensor measurements (blood, soft tissues, etc.). For instance, in US echo imaging, a high lateral spatial resolution as well as a high axial spatial resolution can be obtained, and in tissue displacement v...

Large-scale projects often have several activities which are performed by subcontractors with limited multi-resources. Project scheduling with limited resources is one of the most famous problems in the research operations and optimization cases. The resource-constraint project scheduling problem (RCPSP) is a NP-hard problem in which the activities of a project must be scheduled to reduce the p...

An important problem involves isolating subpopulations of cells defined by protein markers in clinical tissue samples for proteomic studies. We describe a method termed Immunohistochemical staining, laser capture microdissection (LCM) and filter-aided sample preparation (FASP)-Assisted Proteomic analysis of Target cell populations within tissue samples (ILFAPT). The principle of ILFAPT is that ...

Lemniscate chaotic map (LCM) provides a wide range of control parameters, canceling the need for several rounds substitutions, and excellent performance in confusion process. Unfortunately, hardware model LCM is complex consumes high power. This paper presents proposed low power called practical lemniscate (P-LCM) depending on trigonometric identities to reduce complexity conventional model. Th...

Traditional two-dimensional electrophoresis (2-DE) is a wellestablished technique for protein analysis, but its use in identifying changes in protein abundance in tissue samples has been limited by system variability and low sensitivity. These limitations have largely precluded its use to identify protein differences in scarce materials such as those recovered from laser-capture microdissection...