brain death is associated with increased inflammatory cytokines levels and poor graft quality to transplant. we aimed to evaluate the impact of ascorbic acid (aa) on the inflammatory status of brain-dead donors (bdds). forty bdds were randomly divided into two groups. donor treatment (n=20) consisted of 100 mg/kg aa infusion 6 hours before donor operation and subsequent infusion of 100 mg/kg/p6...

background although liver transplantation is the last resort for treating end stage liver diseases, this medical procedure is not available for all needful patients because of inadequate organ supply. therefore, guidelines have been developed by medical experts to regulate the process. some professionals believe that medical criteria are inadequate for organ allocation in all situations and may...

background: bone marrow transplantation is a good therapeutic modality for beta thalassemia. liver complications is one of the major causes of morbidity and mortality following bmt. determination of the factors of liver injury leads to earlier diagnosis after bmt and improves prognosis. materials and methods: we studied 113 major beta thalassemic patients who have been transplanted from 1990- 2...

Globally, an estimated one million deaths occur annually due to complications of cirrhosis. Cirrhosis with end stage liver disease [ESLD] is a leading cause death noncommunicable diseases in Sri Lanka. Non-alcoholic fatty [NAFLD] and alcohol related [ARLD] are the principal causes ESLD cirrhosis Liver transplantation remains only curative treatment for such patients. Multiorgan dysfunction hemo...

Background: Pediatric liver transplant is a complex surgical procedure. Pediatric liver transplantation has evolved over the last two decades into an effective and widely accepted therapy for infants and children. The aim of our report is to review the current state of knowledge and explore the incidence of complications, the involved pathogens among liver recipients to determine the effective ...

background: the implications of cardiac risk stratification before orthotopic liver transplantation (olt) are not well established. we studied the usefulness of myocardial perfusion imaging (mpi) in this scenario. methods: mpi data of 24 patients (9 females), candidates of olt, were collected. they underwent mpi as part of their preoperative risk assessment. mpis were interpreted by 2 nuclear p...

conclusions in our population of cirrhotic patients, treatment of variceal bleeding predisposed the patients to portal vein thrombosis, but hypercoagulable disorders by themselves were not associated with portal vein thrombosis. results there was no statistically significant difference in the assessed hypercoagulable states between patients with or without portal vein thrombosis. a history of p...

â  ba ckground the only curative therapy for end-stage liver disease is transplantation but due to a shortage of available donor livers the waiting list mortality is high. this study aimed to evaluate the outcome and characteristics of patients on the waiting list for liver transplantation in shiraz, southern iran during the period from april 2004 to march 2007. methods medical records of all c...

Liver transplantation (LT) is the treatment of choice for patients with cirrhosis, decompensated disease, acute liver failure, and hepatocellular carcinoma (HCC). In 3–25% cases, an alarming problem chronic cellular rejection after LT, this event can lead to need new or death patient. On other hand, gut microbiota involved in several mechanisms sustaining model “gut–liver axis”. These include m...