Prurigo nodularis (PN) is a benign neurodermatitis of unknown etiology characterized by firm, hyperkeratotic pruritic nodules most commonly localized symmetrically on the bilateral extensor lower extremities. PN represents a primary dermatological condition or a dermatological manifestation of repeated traumatic manipulation secondary to chronic pruritus. One must consider underlying causes of ...

Carrier-depletion based silicon modulators with lateral and interdigitated PN junctions are compared systematically on the same fabrication platform. The interdigitated diode is shown to outperform the lateral diode in achieving a low VπLπ of 0.62 V∙cm with comparable propagation loss at the expense of a higher depletion capacitance. The low VπLπ of the interdigitated PN junction is employed to...

Long-term parenteral nutrition (PN) administration can lead to PN-associated liver diseases (PNALD). Although multiple risk factors have been identified for PNALD, to date, the roles of bile acids (BAs) and the pathways involved in BA homeostasis in the development and progression of PNALD are still unclear. We have established a mouse PN model with IV infusion of PN solution containing soybean...

background: cobalamin deficiency and peripheral neuropathy (pn) are commonly seen in hiv-infected adults. the level of urine methylmalonic acid (umma), a reliable indicator of tissue cobalamin status, was determined in hiv infected subjects with and without pn to establish this association. methods: one hundred and ninety-eight (198) consenting hiv infected subjects with and without pn were rec...

Let Pn be a set of n points on the plane in general position, n ≥ 4. A convex quadrangulation of Pn is a partitioning of the convex hull Conv(Pn) of Pn into a set of quadrilaterals such that their vertices are elements of Pn, and no element of Pn lies in the interior of any quadrilateral. It is straightforward to see that if P admits a quadrilaterization, its convex hull must have an even numbe...

Containing most of the L-selectin and P-selectin glycoprotein ligand-1 (PSGL-1) on their tips, microvilli are believed to promote the initial arrest of neutrophils on endothelium. At the rolling stage following arrest, the lifetimes of the involved molecular bonds depend on the pulling force imposed by the shear stress of blood flow. With two different methods, electron microscopy and micropipe...

Purpose: To compare the outcomes of prognosis of positive surgical margins (PSM) and negative surgical margins (NSM) after partial nephrectomy (PN). We performed this study to assess local recurrence, distant recurrence and survival rates after PN. Materials and Methods: We searched PubMed, Web of science and the Cochrane Library. Three independent reviewers extracted data using a standardized ...

The paper discusses the case histories of three patients who have faced the emotional implications of being initiated onto long-term parenteral nutrition (PN). In each case the patient's personal and family history, relationship to their illness and the presence or relative absence of resentments and grievances have influenced their ability to tolerate the training and the transition to home PN...