Department of Biochemistry, Paulista School of Medicine, Federal University of São Paulo São Paulo/SP, Brazil. Clinical and Toxicological Analysis Department, São Paulo University of Pharmaceutical Sciences Sao Paulo/SP, Brazil. Institute of Mathematics and Statistics, São Paulo University São Paulo/ SP, Brazil. Heart Institute (InCor), São Paulo University Medical School, São Paulo/ SP, Brazil...

objectives: acetaminophen (apap) toxicity is known to be common and potentially fatal. this study aims to investigate the protective effects of hydroalcoholic extract, remaining from crocus sativus petals (csp) against apap-induced hepatotoxicity by measuring the blood parameters and studying the histopathology of liver in male rats. materials and methods: wister rats (24) were randomly assigne...

Preventive effects of acetazolamide (ACZ) on acute mountain sickness (AMS) are well established but effects on exercise performance at high altitude or in hypoxia have been less considered and are still inconsistent. We hypothesized that low-dose ACZ would not impair exercise performance at simulated high altitude. Thus, the aim of this study was to evaluate the interaction between low-dose ACZ...

Objectives: Acetaminophen (APAP) toxicity is known to be common and potentially fatal. This study aims to investigate the protective effects of hydroalcoholic extract, remaining from Crocus sativus petals (CSP) against APAP-induced hepatotoxicity by measuring the blood parameters and studying the histopathology of liver in male rats. Materials and Methods: Wister rats (24) were randomly assigne...

The role of aspirin in women with infertility is controversial and the evidence is inconsistent; some studies have reported benefits in women undergoing IVF whilst others have not. An important gap in the literature was the question of when to start and when to stop aspirin and how long should aspirin be given for. In a 2007 systematic review on the effectiveness of aspirin on IVF outcomes invo...