background: the exposure of cell lines to low-dose irradiation leads to changes at molecular level, which may induce adaptive response. we examined radio-adaptive doses effect on human colorectal adenocarcinoma cell line (ht29) and human fetal fibroblasts (mrc5) cell line followed by hyper and hypo fractionation regimes, with main purpose to decrease cell viability in ht29, and at the same time...

DESCRIPTION Update of the 1996 U.S. Preventive Services Task Force (USPSTF) recommendation on aspirin prophylaxis in pregnancy. METHODS The USPSTF reviewed the evidence on the effectiveness of low-dose aspirin in preventing preeclampsia in women at increased risk and in decreasing adverse maternal and perinatal health outcomes, and assessed the maternal and fetal harms of low-dose aspirin dur...

OBJECTIVES Review of public health perspectives of preeclampsia in developing countries and implications for health system strengthening. METHODS Literature from Pubmed (MEDLINE), AJOL, Google Scholar, and Cochrane database were reviewed. RESULTS The prevalence of preeclampsia in developing countries ranges from 1.8% to 16.7%. Many challenges exist in the prediction, prevention, and managem...

OBJECTIVE To examine the effect of a combination of screening and treatment with low-dose aspirin on the prevalence of early-onset pre-eclampsia (PE). METHODS This was a retrospective analysis of two consecutive cohorts of women screened for early PE. The first cohort was observed to determine whether algorithms developed to screen for PE at 11 to 13 + 6 weeks' gestation could be applied to o...

background: this work investigated the dosimetry limitations of the random and systematic uncertainties of sliding window (sw) intensity modulated radiation therapy (imrt). materials and methods: a varian 21ex linear accelerator, pinnacle3 treatment planning system and radiographic film dosimetry was used. the limitations of the sw were studied using beam modulation ranging from 2 to 100 mu/bea...

abstract introduction:  this study was performed to compare the effects of low-dose interferon beta-1(cinnovex,30 mcg) and high-dose interferon beta-1(rebif,44 mcg) on the reduction of the number and size of plaques in magnetic resonance imaging (mri) in patients with multiple sclerosis (ms). methods and materials: this historical cohort study, which was performed in 2014 in sanandaj (western p...

OBJECTIVE To compare the effect of early administration of aspirin on the risk of preterm and term preeclampsia. METHOD A systematic review and meta-analysis of randomized controlled trials were performed. Women who were randomized to low-dose aspirin or placebo/no treatment at or before 16 weeks of gestation were included. The outcomes of interest were preterm preeclampsia (delivery <37 week...

Meta-analysis of randomized studies on the use of low-dose aspirin in women at high risk of preeclampsia (PE) has demonstrated that if treatment is initiated at ≤16 weeks' gestation, there is significant reduction in the risk of PE [relative risk (RR) 0.47, 95% confidence interval (CI) 0.36-0.62], fetal growth restriction (RR 0.46, 95% CI 0.33-0.64), preterm birth (RR 0.35, 95% CI 0.22-0.57) an...