Dear Editor On September 2018, a case report titled “Squamous cell carcinoma arising from a sebaceous cyst” was published in the “Journal of Surgery and Trauma” (volume 6, issue 2) (1). It was an interesting article; however, I think when dealing about such rare tumors, it is important to be aware of other diseases, such as proliferating trichilemmal cysts (PTC) that may be confused with squam...

IsHII, Y., MORI, M. and FUJIMOTO, T. Immunofluorescence Study of Germinal Centers in Mouse Lymph Nodes during the Secondary Immune Response. Tohoku J. exp. Med., 1970, 102(2), 143-157 An immunofluorescence study carried out on the relationship between the mode of localization of antigen and that of specific antibody and ƒÁ-globulin in the germinal centers of mouse popliteal lymph nodes during t...

Background and Objective: The primary goal of this study is to develop a rigorous understanding ofthe correlation between COX-2 expression and malignant melanoma prognostic factors. Material and Methods: In this cross-sectional study, we analyzed 60 cases of cutaneous malignant melanoma. The related stained slides were reviewed by two pathologists. The re...

Secondary lymphoid organs including lymph nodes are composed of stromal cells that provide a structural environment for homeostasis, activation and differentiation of lymphocytes. Various stromal cell subsets have been identified by the expression of the adhesion molecule CD31 and glycoprotein podoplanin (gp38), T zone reticular cells or fibroblastic reticular cells, lymphatic endothelial cells...

To the Editor: Interferons are widely used in the treatment of both malignant and nonmalignant diseases. One rare complication, attributable to the immunomodulatory effect of interferon (IFN) treatment is the triggering or exacerbation of sarcoidosis [1]. We present the scintigraphic and radiographic imaging findings of a patient that developed sarcoidosis with bone involvement mimicking metast...

The study assessed the validity of the lymph node "roundness index" (RI) in the evaluation of enlarged lymph nodes of the neck. A total of 107 subjects were included in the prospective study, and 135 enlarged lymph nodes were examined. All the subjects were examined clinically and sonographically, the lymph node roundness index was determined, and soon after the nodes was surgically removed and...

L1 is an immunoglobulin superfamily adhesion molecule highly expressed on neurons and involved in cell motility, neurite outgrowth, axon fasciculation, myelination, and synaptic plasticity. L1 is also expressed by nonneural cells, but its function outside of the nervous system has not been studied extensively. We find that administration of an L1 monoclonal antibody in vivo disrupts the normal ...