نتایج جستجو برای: method validation
تعداد نتایج: 1764679 فیلتر نتایج به سال:
In recent years, cleaning validation has achieved a position of increasing in the pharmaceutical industry. It provides assurance to the cleaning procedure that ensures equipment is consistently cleaned from the product, detergent and microbial residues to an acceptable level to avoid cross-contamination and adulteration of drug product with other active ingredients. The aim of this study was to...
This paper defines a method that can be used for validating knowledge-based systems (KBS) throughout their entire lifecycle. Method’s name is MAVERICK. It stands for Method for Automated Validation Embedded into the Reusable and Incremental CommonKADS. The lack of suitable, rigorous and general validation methods has become a serious obstacle to user acceptance of KBS for critical applications....
resolution of binary mixtures of theophylline (theo), montelukast (mkst) and loratadine (lora) with minimum sample pretreatment and without analyte separation has been successfully achieved by multivariate spectrophotometric calibration, together with partial least-squares (pls-1), principal component regression (pcr) and hybrid linear analysis (hla). data of analysis were obtained from uv–vis ...
background: logistic discriminant method was applied to differentiate malignant from benign in a group of patients with proved breast lesions on the basis of ultrasonic parameters. materials and methods: our database include 273 patients' ultrasonographic pictures consisting of 14 quantitative variables. the measured variables were ultrasound propagation velocity, acoustic impedence and at...
soil moisture retention curve is one of the soil hydraulic prosperities which its direct measurement is time consuming and expensive. therefore, indirect methods such as developing pedotransfer functions have been used to predict this characteristic from soil readily available or easily measurable data. in this study, multiple linear regression method was used to develop point pedotransfer func...
Gabapentin is an anticonvulsant widely used in the treatment of epilepsy.An accurate and validated spectrophotometric method was developed as an alternative method to determine gabapentin in pharmaceutical products. This is a simple, accurate, precise, selective and visible spectrophotometric method. The method is based on the measurement of drug absorbance as a result of yellow solution format...
a fast and simple modified quechers (quick, easy, cheap, rugged and safe) extraction method based on spiked calibration curves and direct sample introduction was developed for determination of benzo[a]pyrene (bap) in bread by gas chromatography-mass spectrometry single quadrupole selected ion monitoring (gc/ms-sq-sim). sample preparation includes extraction of bap into acetone followed by clean...
background: the present study was performed to develop a scoring system for predicting cure status in patients with cutaneous leishmaniasis (cl). materials and methods: this study included 199 patients with cl from skin diseases and leishmaniasis research center (isfahan, iran). data were collected as longitudinal in each visit of patients. we applied ordinal logistic generalized estimating equ...
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