Molecular Inflammation Research Center for Aging Intervention (MRCA), College of Pharmacy, Pusan National University, Busan 609-735, Republic of Korea Graduate School of Science and Engineering for Research, University of Toyama, Toyama 930-8555, Japan Faculty of Pharmaceutical Sciences, Nagasaki University, Nagasaki 852-8131, Japan Department of Physiology, The University of Texas Health Scien...

where f(t |Θ) is the probability density of the coalescent time. Assuming free recombination between loci, the full likelihood is a product of each locus likelihood. In order to determine the likelihood we must determine the density f(t |Θ) for coalescent of two samples in the IM model. Wang and Hey (2009) find the time to the MRCA by explicitly integrating over all possible sample paths in the...

Recent statistical and computational analyses have shown that a genealogical most recent common ancestor (MRCA) may have lived in the recent past [Chang, J.T., 1999. Recent common ancestors of all present-day individuals. Adv. Appl. Probab. 31, 1002-1026. 1027-1038; Rohde, D.L.T., Olson, S., Chang, J.T., 2004. Modelling the recent common ancestry of all living humans. Nature 431, 562-566]. Howe...

Chemical differences between mid-ocean ridge basalts (MORBs) and ocean island basalts (OIBs) provide critical evidence that the Earth's mantle is compositionally heterogeneous. MORBs generally exhibit a relatively low and narrow range of (3)He/(4)He ratios on a global scale, whereas OIBs display larger variability in both time and space. The primordial origin of (3)He in OIBs has motivated hypo...

BACKGROUND Angiogenesis occurs by at least three mechanisms: sprouting, intussusception and elongation. Studies to date have failed to identify the mechanisms or timing of endometrial angiogenesis during the menstrual cycle. The aim of this study was to determine if vessel elongation plays a role in human endometrial angiogenesis. METHODS Forty-nine full thickness endometrial sections from 27...

We consider a continuous population whose dynamics is described by the standard stationary Fleming-Viot process, so that the genealogy of n uniformly sampled individuals is distributed as the Kingman n-coalescent. In this note, we study some genealogical properties of this population when the sample is conditioned to fall entirely into a subpopulation with most recent common ancestor (MRCA) sho...

Identifying characteristics of foraging activity is fundamental to understanding an animals' lifestyle and foraging ecology. Despite its importance, monitoring the foraging activities of marine animals is difficult because direct observation is rarely possible. In this study, we use an animal-borne imaging system and three-dimensional data logger simultaneously to observe the foraging behaviour...