OBJECTIVE Recurrent headaches and ADHD are prevalent in the pediatric population. Herein, we assess if ADHD is comorbid to headaches overall, to headache subtypes (e.g., migraine), and to headache frequency. METHOD Informed consent and analyzable data were obtained for 5,671 children aged 5 to 12 years (65.9% of the target sample). Parents and teachers were interviewed using validated questio...

Migraine headaches are among the most common headache disorders seen in various practices. The prevalence of migraine headaches is 18% in women and 6% in men. While millions of Americans suffer from migraine headaches, roughly 3%-13% of identified migraine patients are on preventive therapy, while an estimated 38% actually need a preventive agent. The challenge among physicians is not only when...

During the past few decades, much controversy has surrounded the pathophysiology of migraine. Cortical spreading depression (CSD) is widely accepted as the neuronal process underlying visual auras. It has been proposed that CSD can also cause the headaches, at least in migraine with aura. We describe three patients, each fulfilling the International Headache Society criteria for migraine with a...

Background and objectives: Migraine is the seventh most common cause of disability among all ailments according to the World Health Organization. Despite the availability of some medicines for prevention of migraine, their complications are a cause for concern. Traditional system of medicine and use of medicinal herbs can be beneficial in management of migraine. “Gol-e-ghan...

CONTEXT Botulinum toxin A is US Food and Drug Administration approved for prophylactic treatment for chronic migraines. OBJECTIVE To assess botulinum toxin A for the prophylactic treatment of headaches in adults. DATA SOURCES A search of MEDLINE, EMBASE, bibliographies of published systematic reviews, and the Cochrane trial registries between 1966 and March 15, 2012. Inclusion and exclusion...

Gary A. L’Europa MD, FASH  wHat CliniCal findings are Most useful for differentiating aMong tHe various types of HeadaCHes? When asked to comment on this topic I immediately thought of the advice that Seymour Diamond, founder of the Diamond Headache Center and the godfather of headache gave to his daughter Merl when she succeeded him as director, “Merl, it’s all migraine.” About 90% of all the...

OBJECTIVES The aims of this study were to investigate the prevalence of osmophobia among primary headaches, evaluate the association between osmophobia and the characteristics of patients and their headaches, and assess the usefulness of this symptom for diagnosing migraine. METHODS This was a cross-sectional study in a primary care unit. Patients who consecutively sought medical attendance i...

Background Hypoxia causes secondary headaches such as high-altitude headache (HAH) and headache due to acute mountain sickness. These secondary headaches mimic primary headaches such as migraine, which suggests a common link. We review and discuss the possible role of hypoxia in migraine and cluster headache. Methods This narrative review investigates the current level of knowledge on the relat...