Lithium(I) and uranium(VI) amido-tethered Bu(t)-substituted N-heterocyclic carbene (NHC) complexes exhibit very distorted metal-carbene bonds; the corresponding magnesium(II) and mesityl-substituted NHC uranium(VI) complexes are undistorted; the distortion does not affect the ligand binding strength, suggesting a dominance of electrostatic character in closed-shell electropositive metal-carbene...

Reactions of 10-benzo[h]quinolyllithium with a series of organosilanes led to the formation of neutral pentacoordinate complexes. The diethynyl-substituted complex was able to be converted to di(arylethynyl)-substituted ones by the Sonogashira-Hagihara coupling reaction. Electronegative substituents shortened N-Si distances and enhanced fluorescence intensity from the complexes.

The present study aims to synthesis and full characterization of two new pentacoordinated isothiocyanate iron(III) mixed ligand complexes featuring dianionic (N2O2)2? tetradentate Schiff-base ligands unsymmetrically substituted by either a pair acceptor (4-fluorophenyl nitro) or donor (ferrocenyl methoxy) substituents. neutral complexes3 4 were prepared in very good yields (~90 %) upon reaction...

This is a report of the studies conducted on synthesis, spectral, biological viz. antibacterial and antitumorous activities some Copper complexes synthesized from multidentate thiosemicarbazone ligand, HL2. based reaction between secondary amine viz.N-phenyl piperazine an N-substituted heterocyclic ketone 2-Benzoylpyridine. The ligand exhibits mode coordination through N,N,S donor atoms in copp...

The malaria organism Plasmodium falciparum detoxifies heme released during degradation of host erythrocyte hemoglobin by sequestering it within the parasite digestive vacuole as a polymer called hemozoin. Antimalarial agents such as chloroquine appear to work by interrupting the heme polymerization process, but their efficacy has been impaired by the emergence of drug-resistant organisms. We re...

The reaction of Fe(NCS)3 prepared in situ in MeOH with Hqsal-X (Hqsal-X = 5-X-N-quinolylsalicylaldimine) in CH2Cl2 yields the FeIII complexes, [Fe(qsal-X)2]NCS·solvent (X = F 1; X = Cl, 2, Br, 3 solvent = MeOH; X = I, solvent = 0.25CH2Cl2·0.5MeOH 4) in moderate to good yields. IR spectroscopy confirms that NCS− acts as a counteranion only and that the qsal-X ligand is bound to the FeIII centre....

The reaction of the oxidovanadium(V) complexes with N,N-dimethylhydrazine was demonstrated to afford the corresponding vanadium(V) dimethylhydrazido complexes. The substituent at the 3-position of the tris(2-hydroxyphenyl)amine ligand was found to influence the electronic environment of the vanadium center. The crystal structure of the non-substituted vanadium(V) dimethylhydrazido complex exhib...

In an effort to discover potential alternatives to the anti-cancer drug cisplatin, the synthesis of gold(III) polypyridyl coordination complexes was pursued. Specifically, this report describes the synthesis and characterization of a series of 2,9-dialkyl-1,10-phenanthroline (Rphen) gold(III) coordination complexes (R = n-butyl, sec-butyl, and tert-butyl). Due to the steric hindrance imparted b...