Flunarizine, a calcium channel antagonist of the piperazine class, has been labeled with the positron-emitter 18F.4-[18F]Fluoro-4-fluorobenzhydryl chloride was prepared in three steps from no-carrier-added [18F]fluoride ion, and used in the alkylation of N-cinnamylpiperazine to give [18F]flunarizine in 13% radiochemical yield (from [18F]fluoride).

UNLABELLED A novel synthetic approach to 6-(18)F-fluoro-3,4-dihydroxy-L-phenylalanine ((18)F-DOPA), involving the nucleophilic substitution of a diaryliodonium salt precursor with non-carrier-added (18)F-fluoride, yielded a product with a specific activity that was 3 orders of magnitude higher than the product of the conventional synthesis method, involving an electrophilic substitution of a tr...

The International Forum on Translation Technology will be held on the theme of cooperative work between humans and the computer. As an example of the cooperative work, the present situation and prospects for the machine translation value-added network (MT-VAN) service will be described below. In the MT-VAN, users, the machine translation systems and the translators are satisfactory linked by th...

Digital phase reconstruction of directly detected minimum (MP) optical signals using the Kramers-Kronig (KK) algorithm has recently drawn attention because its low hardware complexity. Only a single photodiode is required to detect intensity signal and KK relations are used retrieve information. To make sure by MP, carrier tone needs be inserted. In this work, we digitally add at transmitter, o...