background and objective: sleep-disordered breathing (sdb) is associated with increased morbidity and mortality in patients with heart failure (hf). we assessed the prevalence and the pattern of sdb in hf patients who were candidates for heart transplantation. materials and methods: twenty heart transplantation patients with ventricular ejection-fraction < 25% were recruited consecutively in a ...

background: chronic obstructive pulmonary diseases (copd) are planned to rank fifth in burden of disease and third with respect to mortality by 2020. carrying out research regarding different aspects of copd is mentioned as important health priorities by academic institutions and governments. the burden of lung disease (bold) initiative was designed a decade ago to develop robust models that ca...

pompe disease, also termed glycogen storage disease type ii or acid maltase deficiency, caused by deficient activity of acid alpha-glucosidase (gaa), the glycogen degrading lysosomal enzyme. as a result, massive lysosomal glycogen deposits in the numerous organs including the muscles. in pompe disease weakness of truncal muscles is a prominent presentation which results in respiratory failure a...

Forty-five patients with chronic obstructive pulmonary disease were studied to compare the acute effects of ipratropium bromide (60 µg), salbutamol (300 µg) and placebo (3 puffs) on the forced expiratory volume in 1 sec (FEV 1) and forced vital capacity (PVC). Ipratropium bromide produced a significantly greater improvement than salbutamol in both FEV1 and FVC at 15,60 and 180 minutes afte...

background: considering the effectiveness of craniofacial photographic analysis for diagnosis and management of obstructive sleep apnea-hypopnea syndrome (osahs) as well as ethnic differences in indexes measured by this method, this study designed to compare the surface facial dimensions, including nose width, intercanthal width and mandibular width of iranian patients with mild, moderate and s...

introduction: chronic obstructive pulmonary disease (copd) secondary to sulfur mustard gas poisoning, known as mustard lung, is a major late pulmonary complications in chemical warfare patients. serious comorbidities like dyslipidemia are frequently encountered in copd. the aim of this study was to measure the serum lipid profile and evaluate the relation of lipid parameters with the severity o...

materials and methods weighted logistic regression models were used for the analysis of 1,248 cases and 39,995 controls from the 2005 california health interview survey (chis). results the prevalence of spd was 10% in cases and 4% in controls, respectively. the percentages of past and current smoking were higher in cases than controls (50% vs. 24% and 27% vs. 15%, respectively). after adjusting...

the purpose of this study was to examine the effect of intravenous magnesium sulfate on patients with copd exacerbation requiring hospitalization. in this randomized clinical trial 30 patients with copd exacerbation were studied. patients were randomly assigned to group a (case) who concurrent with standard therapy received 2g magnesium sulfate in normal saline infused in 20 minutes on days one...

background: postoperative cognitive dysfunction (pocd) has been an important complication of cardiac surgery over the years. neurocognitive dysfunction can affect quality of life and lead to social, functional, emotional, and financial problems in the patient’s life. to reduce pocd, we sought to identify the association between cognitive dysfunction and perioperative factors in patients undergo...

background and objective: obstructive sleep apnea (osa) is the most common type of sleep-disordered breathing. multivariable apnea prediction (map) index consists of three questions about the frequency of osa symptoms plus body mass index (bmi), age and sex that categorizes the patients to low and high risk for osa using a formula. objective map index was calculated by discounting the questions...