background and objective : obstructive sleep apnea (osa) through hypoxia and reoxygenation periods leads to oxidative stress, endothelial dysfunction, and activation of inflammatory cycles, which eventually may cause disorder in vasa nervorum, and peripheral neuropathy in hearing pathway. in this study, we aimed to evaluate the effect of severe sleep apnea on hearing function. materials and met...

liver injury occurs with many drugs; therefore, a thorough work up is important for establishing the diagnosis. we report a case of trifluoperazine-induced cholestatic jaundice. a 44-year old male with schizoaffective disorder developed an increase in liver enzymes and jaundice after starting treatment with trifluoperazine. workup for other potential etiologies was negative.

Background: There is limited evidence regarding the risk factors and nutritional patterns in patients with premature coronary artery disease (PCAD). This study aims to investigate the relationship between different dietary patterns and risk factors in patients with PCAD. Methods: This cross-sectional study was conducted on PCAD patients, including men younger than 55 years and women younger tha...

conclusions osa was associated with depression among the elderly patients. given the high prevalence of osa in older adults, implementation of screening methods is necessary to identify people at high risk of osa. patients and methods a total of 350 home residing elderly took part in this case-control study. the participants were selected using clustering method. all cases were divided into two...

background obstructive sleep apnea (osa) is a common sleep disease. it is associated not only with hypertension but also with other cardiac complications. thus, the early detection of cardiac disorders is very useful. objectives we sought to evaluate different echocardiographic parameters. patients and methods this cross-sectional study was done on 55 patients with osa. the patients were divide...

context worldwide prevalence of respiratory diseases, suffering from such diseases, and heavy cost of treatment, which all may result from lack of etiological understanding of these diseases in modern medicine, were the main factors to conduct the current study. in the present study, the causes and symptoms of asthma were evaluated and compared with those of some other respiratory diseases. ira...

chronic obstructive pulmonary disease (copd) is associated with a chronic inflammatory response in airways and lung parenchyma that results in significant morbidity and mortality worldwide. cigarette smoking considered as an important risk factor plays a role in pathogenesis of disease. pneumocystis jirovecii is an atypical opportunistic fungus that causes pneumonia in immunosuppressed host, al...

introduction:the overlap syndrome, consisting ofobstructive sleep apnea hypopnea syndrome (osahs) and chronic obstructvie pulmonary disease (copd) is a major problem in copd patients. oshas corresponds to the likelihood of systemic hypertension.the present study was aimed to evaluate the association between apnea-hypopnea index and diastolic blood presssure (dbp) in overlap  patients. materials...