BACKGROUND Previous studies showed that octacalcium (OCP) collagen composite (OCP/Col) can be used to repair human jaw bone defects without any associated abnormalities. The present study investigated whether OCP/Col could be applied to dental implant treatment using a dog tooth extraction socket model. METHODS The premolars of dogs were extracted; each extraction socket was extended, and tit...

Background. This in vitro study compared the effects of mineral trioxide aggregate (MTA), calcium enriched mixture(CEM) cement, Biodentine (BD) and octacalcium phosphate (OCP) on the viability of human gingival fibroblasts (HGFs). Methods. After completion of the setting time of the materials under study, fibroblasts were placed in 24-well insert platesand 1 mg of each material was added to the...

This study hypothesized that distant octacalcium phosphate (OCP) scaffolds may enhance osteocyte differentiation in newly formed bone matrices. The results obtained were compared with those of Ca-deficient hydroxyapatite (OCP hydrolyzate, referred to as HL hereafter). Granular OCP and HL, 300–500 µm diameter, implanted critical-sized rat calvarial defects for eight weeks subjected histology, im...

introduction: this in vitro study assessed and compared the cytotoxicity of mineral trioxide aggregate (mta), calcium-enriched mixture (cem) cement, biodentine (bd) and octacalcium phosphate (ocp) on stem cells of the human apical papilla (scap). methods and materials: scaps were isolated from two semi-impacted third molars. the cells were cultured in wells of an insert 24-well plate and were t...