n engl j med 359;20 www.nejm.org november 13, 2008 2172 moderately obese subjects in our study was identical to that reported in a recent meta-analysis on long-term pharmacotherapy for obesity.2 In response to Ornish’s letter: the low-carbohydrate diet was based on Atkins’s book, although we encouraged the study participants to consume a variety of protein and fat sources to maintain successful...

Abstl'act. Along with increased life ~xpcctancy, sllccessful aging and possibilities for increasing well-being in old age have become important research topics in recent years. T!1(~ present study (a) examines the relationship between satisfaction in several life domains (\vith respect to family. friendships, and health) and general life satisfaction of oldcr adult women in Germany. and (b) dct...

BACKGROUND Decreases of strength and speed of muscle contraction are considered major causes of functional impairments in older people. However, the age-related changes in grip force-generating capacity are not clear. The purpose of this study was to measure the parameters of the explosive grip force test and to compare the differences between young and older women. METHODS Thirty healthy you...

The nutritional requirements of older women is an area of great interest because the extended life expectancy leads to an increase in women living into their 80s, 90s, and longer. The recommended dietary allowances (RDAs) and dietary reference intakes (DRIs) are not specific for women living to advanced ages, and little research has been conducted specifically on the micronutrient needs of elde...

As the proportion of the population age 65 and over continues to grow--to a projected 20.5% or 77.2 million by the year 2040--tracking the quality, access, and receipt of care for older women becomes more important, since the majority of older citizens are women. This article establishes a rough baseline for the quality of care, primarily preventive care, received by older women compared to old...

Breast cancer is a major cause of cancer-related deaths among older women, aged 65 years or older. Screening mammography has been shown to be effective in reducing breast cancer mortality in women aged 50-74 years but not among those aged 75 years or older. Given the large heterogeneity in comorbidity status and life expectancy among older women, controversy remains over screening mammography i...

BACKGROUND Estradiol (E(2)) concentration is preserved in older reproductive-aged women despite a decrease in follicle number and androstenedione (AD) levels. We hypothesized that increased aromatase activity accounts for E(2) preservation in older women. METHODS Older (36-46 years; n = 11) and younger (21-35 years; n = 10) women with 25- to 35-day menstrual cycles participated in a parallel ...