We present a model case study of the activity of aqueous extract of Hericium erinaceus fresh fruit bodies in promoting functional recovery following crush injury to the peroneal nerve in adult female Sprague-Dawley rats. The aim was to explore the possible use of this mushroom in nerve repair. The activities of aqueous extract were compared to activities exhibited by mecobalamin (vitamin B12), ...

Oxidation of low-density lipoprotein (LDL) has been strongly suggested as the key factor in the pathogenesis of atherosclerosis. Mushrooms have been implicated in having preventive effects against chronic diseases due especially to their antioxidant properties. In this study, in vitro inhibitory effect of Hericium erinaceus on LDL oxidation and the activity of the cholesterol biosynthetic key e...

background: recently there is a high tendency among exotic pet owners for keeping hedgehogs. this mammal can transfer some significant zoonotic patho-gens to human. hence, the present study was conducted for the first time to pre-pare a list of helminth parasites of hedgehogs ( erinaceus concolor ) in north of iran. methods: ten (four males and six females) road killed hedgehogs were collected ...

background : hedgehogs are small, nocturnal mammals which become popular in the world and have important role in transmission of zoonotic agents. thus, the present study aimed to survey ectoparasite infestation from april 2010 to december 2011 in urban and suburban parts of urmia and tabriz cities, northwest of iran. methods : a total number of 84 hedgehogs (40 females and 44 males) were examin...

Due to the unpleasant side effects of long-term use of commercially available drugs, the discovery and development of natural therapeutic agents to prevent life-debilitating diseases is urgently needed. In the present study, the optimization of medium composition for maximum mycelial biomass and bioactive compounds production by Hericium erinaceus was studied using response surface methodology ...

A single-band protein (HEP3) was isolated from Hericium erinaceus using a chemical separation combined with pharmacodynamic evaluation methods. This protein exhibited immunomodulatory activity in lipopolysaccharide-activated RAW 264.7 macrophages by decreasing the overproduction of tumor necrosis factor-α, interleukin (IL)-1β, and IL-6, and downregulating the expression of inducible nitric oxid...