Background: Based on the studies, variation in the mitochondrial DNA (mtDNA) copy number in peripheral blood leukocytes is associated with increased susceptibility to diseases including cancer. Opiate abusers are at high risk for diseases. In this study, we measured the mtDNA copy number in peripheral blood leukocytes in a group of opiate abusers compared with those in healthy individuals. Met...

historically, opium was used as a potent analgesic and to treat dyspnea and cough. it is documented that opium can increase exercise tolerance and relieve breathlessness. however, its overdose can suppress respiratory centers. the purpose of this study was to evaluate effects of opium on spirometric lung volumes.the study was done on two groups of patients referred to the lung clinic of labbafi...

introduction: many studies have revealed that drug addicted individuals exhibit impaired performance on executive function tests but a few studies have been conducted on executive functions of drug addicts in iran. to contribute to this understanding, the present study was designed to assess some domains related to executive functions including cognitive flexibility, attention and speed of ment...

Background: The risk of infectious, autoimmune and immunodeficiency diseases and cancers rise in opioid addicts due to changes in innate and acquired immune responses. Three types of opioid receptors (К،δ،μ) are expressed on the surface of lymphocytes and mononuclear phagocytes. The present study was designed to examine the effects of different concentrations of opium on the secretion of some c...

objectives the aim of this study was to evaluate the biological effects of opium on the number of peripheral blood cells and red blood cells (rbcs) indices in diabetic rats. materials and methods peripheral blood samples were collected from diabetic, opium-addicted, diabetic opium-addicted and normal male and female rats and hematological parameters were measured. results the mean number of whi...

هديكچ فده : و فرصـم عـلو تدـش ناـيم طابترا يسررب فده اب شهوژپ نيا صخاش هـب ناداـتعم يلـصا هورگ هس رد يرگشناكت ياه رد ينوـيفا داوـم ناريا ) كايرت و كارك ،نييوره ( تسا هدش ماجنا . شور : 77 يندومزآ هورگ هس رد داتعم درم : فرصم يقاشـنتسا و يـقيرزت نييورـه هدـننك ) 37 رفن ( فرصم ، ينيخدت كارك هدننك ) 17 رفن ( ينيخدت كايرت و ) 23 رـفن ( هب هـمين هبحاصم كي كمك رايعم اـب قـيبطت و هتفايراتخاـس ر...

abstract  introduction: addiction to opioids is a major health challenge in the world today. a few studies have addressed the effects of these substances and the wrong beliefs surrounding their use. this study was designed to compare plasma lipid peroxidation levels, blood lipids, fasting blood sugar (fbs), and glycosylated hemoglobin (hba1c) in opium addicts and non-addict control subjects. me...

BACKGROUND Iran is one of the major consumers of opium and opiate substances in the world. Addiction has become a very important issue in the 21st century and an urgent one in Iran. The consumption of this substance leaves a variety of impacts on the human body. The goal of this study is to investigate the changes of the biochemical parameters derived from opiate substances in addicts during th...