ABSTRAK
 Sekitar 80-90% pasien cystic fibrosis akan mengalami pancreatic insuffiency. Keadaan ini menyebabkan terjadinya malabsorpsi lemak dan protein berpengaruh pada status nutrisi dari pasien. Terapi insufficiency adalah dengan pemberian enzyme replacement therapy (PERT) untuk meningkatkan absorpsi juga fibrosis. Tujuan kajian sistematis mengetahui efikasi keamanan terapi PERT yang sehi...

The announcement of the 1978 Lasker Award for Basic Medical Research has created two controversies. No one argues with the choice of the three winners-Solomon H. Snyder (Johns Hopkins University), John Hughes (Imperial College of Science and Technology. London), and Hans Kosterlitz (University of Aberdeen) —who were honored for the discovery of opiate receptors and enkephalins, opiate-like subs...

Most studies of project time estimation assume that (a) activity times are mutually independent random variables; many also assume that (b) path completion times are mutually independent. In this paper, we subject the impact of both these assumptions to close scrutiny. Using tools from multivariate analysis, we make a theoretical study of the direction of the error in the classical PERT method ...