Fe3O4 nanoparticles were employment as an efficient and magnetically separable Nano catalyst for the synthesis of amides via one-pot Beckmann rearrangement of ketones under solvent-free conditions. Various secondary amides were synthesized by this method in moderate to good yields. The catalyst showed high thermal stability and was recovered and reused at least five times without any considerab...

Chiral amines are a highly important class of compounds for which powerful synthetic approaches remain in high demand. Herein, we report an unprecedented method the preparation chiral α-amino amides from cheap and abundant starting materials. Our strategy relies on direct amination using enantiopure sulfinamides. It involves [2,3]-sigmatropic rearrangement key sulfonium intermediate. We further...

A sustainable enzymatic strategy for the preparation of amides by using Candida antarctica lipase B as biocatalyst and cyclopentyl methyl ether a green safe solvent was devised. The method is simple efficient it produces with excellent conversions yields without need intensive purification steps. scope reaction extended to 28 diverse four different free carboxylic acids seven primary secondary ...

this paper reports on preparation of polyamide membrane with addition of silver nanoparticles (agnps). agnps act as antibacterial agents that are less susceptible to membrane’s biofouling by interfacial polymerization (ip) method. agnps was synthesized via green route which has been reported previously. attenuated total reflectance-fourier transform infrared spectroscopy (atr-ftir), field emiss...

Palladium-catalyzed synthesis of nitriles from amides has been described. Two similar, but complementary reaction conditions have been identified to convert various amides including α,β,γ,δ-unsaturated amides, cinnamides, aromatic amides and alkyl amides to the corresponding nitriles in good to excellent yield.

Imidazole N-oxides are attractive starting materials for the preparation of complex molecules containing an imidazole ring. Dipolar cycloaddition between 1,1-difluoroalkenes and bearing a chiral auxiliary performed in presence oxygen or nitrogen nucleophiles was found to provide access esters amides 2-azaheteroaryl substituent at α position ring as mixtures diastereomers that, most cases, readi...

The binding of metal ions to amide groups has been a subject of increasing interest over the past two decades largely because many of these reactions provide simple models for much more complex metalpeptide systems and enzymes . The interaction of different metal ions with diversely substituted amides has been intensively studied2−5. We are interested in studying the coordinating properties of ...

The diastereoselective conjugate addition of homochiral lithium amides to methyl 4-(N-allyl-N-benzylamino)but-2-enoate has been used as the key step in a simple and efficient protocol for the preparation of 3,4-substituted aminopyrrolidines. This protocol provides a complementary and stereoselective route to both anti- and syn-3-amino-4-alkylpyrrolidines as well as anti- and syn-3-hydroxy-4-ami...