The potential for fast and specific process optimization by functional prototyping with 3D printed reactors was shown a known continuous emulsion polymerization in modular setup. Three tubular reactors, two static mixing elements continuously stirred tank reactor (CSTR) were from polylactic acid. Thermal imaging of the allows to map basically adiabatic progress redox-started radical space-resol...

The purpose of present research work is to develop gastro retentive formulation for Moxifloxacin using various release retardants. Moxifloxacin, novel synthetic fluoro quinolone, antibacterial agent. Floating tablets of Moxifloxacin. HCl were prepared using variable amounts of HPMCK4M, HPMCK15M and HPMCK100M with effervescent mixtures by direct compression technique. Totally 9 formulations were...

The present research work is concerned with the effects of optimum process variables in elevated temperature hydro-mechanical deep drawing of 5052 aluminum alloy. Punch-workpiece and die-workpiece friction coefficients together with the initial gap between the blank holder and matrix were considered as the process variables which, in optimization terminology, are called design parameters. Since...

a r t i c l e i n f o Keywords: Continuous powder mixing Statistical analysis ANOVA Homogeneity Residence time In this paper we examine the effect of rotation rate, mixing angle, and cohesion on the powder residence time and the content uniformity of the blend exiting from two continuous powder mixers. In addition, differences in mixing performance between the two blenders are examined. Analysi...

There are several method for forming bulk material, such as forging, rolling and extrusion. Every of these methods have advantages and dis-advantages of their selves. Forging process is one of the most common of them that include a die, press and in some case heater with controlling system, and has a special place in automotive, military and aerospace industries due uniformity of the final prod...

due to the scarcity of water resources, the need for sustainable development of drip irrigation tape is essential in iran. a number of drip irrigation tape systems used in sugar beet fields of isfahan and chahar mahal va bakhtiari provinces were evaluated and were compared with furrow irrigation methods in two consecutive years. the actual water use efficiency (wuesy, wuewsy) in lower quarter, ...

This inspection guide provides information regarding the inspection and evaluation of the manufacturing and control processes used to manufacture solid oral dosage form pharmaceutical products. This document provides guidance for the FDA investigator and promotes uniformity and consistency during the inspection and evaluation of the validation of the solid oral dosage form manufacturing and con...

In the pharmaceutical industry high hear granulation is a commonly used process step in the production of a solid formulation. Because of regulatory guidelines and product quality assurance, an important granule requirement is homogeneity. However, often granule inhomogeneity is observed, expressed as a granule size-dependent variation in composition of the granules [1-4]. As a consequence of s...